Pancreas Islet Transplantation Type I

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SINGLE-DONOR PANCREAS ISLET TRANSPLANTATION PROCEDURE SHOWS PROMISE FOR PATIENTS WITH TYPE 1 DIABETES
CHICAGO—Patients with type 1 diabetes who received islet transplantation from a single donor pancreas were insulin independent one year later, according to a study in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

Bernhard J. Hering, M.D., of the University of Minnesota, Minneapolis, and colleagues conducted a study to assess the effectiveness and safety of islet transplantation from a single pancreas. The trial was conducted from July 2001 to August 2003 and enrolled eight women with type 1 diabetes. During the trial there were no serious, unexpected, or procedure- or immunosuppression-related adverse events. All eight recipients achieved insulin independence and freedom from hypoglycemia. Five remained insulin-independent for longer than 1 year. The researchers concluded “These findings may suggest a distinct advance in islet transplantation, further study in a larger population with longer follow-up will be critical to assess the risk-benefit ratio of this emerging therapeutic option.”

Full Article
http://jama.ama-assn.org/cgi/content/short/293/7/830

Other sources
http://care.diabetesjournals.org/cgi/content/full/26/suppl_1/s120

 

Another item on the Today programme this morning shortly after 6.00am regarding the British patient at King's College Hospital was underwent successful implant surgery for Type I diabetes. To listen you need Real Player which you can download from the BBC site.

http://www.bbc.co.uk/radio4/today/listenagain/

and

http://news.bbc.co.uk/1/hi/health/4330717.stm