Chilblains in Children

NewsBot · Jan 30, 2013

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Major cluster of chilblain cases in a cold dry Western Australian winter
Nicholas Larkins, Kevin J Murray
Journal of Paediatrics and Child Health (online first)

Aim
Primary chilblains are an idiopathic cold-induced vasculopathy affecting the soft tissues of the hands and feet. Secondary chilblains occur in different forms of vasculitis and chronic autoimmune connective tissue disorders. Idiopathic chilblains are rarely reported in children and may generate significant anxiety to doctors and patients. We describe a cluster of idiopathic chilblains encountered over the winter of 2010 in Perth, Western Australia.

Methods
This is a retrospective review of patients identified from a prospectively compiled database of all new cases seen in our department. Data on history, examination, investigations, prescribed treatments and outcomes were collected.

Results
Thirty-two patients with isolated idiopathic chilblains were included, including 20 females and 12 males with a median age at onset of 13.5 years. Lesions were papular with signs of peripheral vasoconstriction causing acrocyanosis, and uncomfortable due to pain and/or pruritis in most. Thickening of the small joints was common where lesions involved these areas. Ulceration of lesions also occurred in some. One patient required hospitalisation for secondary bacterial infection. Most received some form of treatment including non-steroidal anti-inflammatory drugs, prednisolone or nifedipine. Most patients improved spontaneously with warmer weather or responded to cold protection advice. All had resolved completely by late spring (November).

Conclusion
Our cluster of chilblains was associated with an unusually cold winter in Perth 2010. It is the largest series reported in the literature, suggesting that chilblains may be more common than previously thought. Chilblains are almost always benign in nature and patients are systemically well and usually need no further investigation and only symptomatic treatment. Prompt recognition can avoid excessive investigation and anxiety, allowing appropriate simple advice and treatment.
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Admin2 · Jan 30, 2013

Related threads:
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Pathophysiology of Chilblains
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Chilblains / perniosis

Bug · Feb 1, 2013

Fascinating! I have often thought about doing this in winters in Melbourne as I have my 3rd, 4th or 5th kid in for the week with chilblains.

Poor kids, great study. Now if we could work out how to stop it while still keeping kids active in a cold wet winter.

NewsBot · Feb 23, 2013

Chronic chilblains: the clinical presentation and disease course in a large paediatric series
Padeh S, Gerstein M, Greenberger S, Berkun Y.
Clin Exp Rheumatol. 2013 Feb 15.

OBJECTIVES:
Children often present during winter with painful, red-purple swollen fingers and/or toes, usually misdiagnosed as Raynaud's phenomenon. Pernio, or chronic chilblains, is a localised inflammatory lesion of the skin resulting from an abnormal response to cold. The aim of this study was to better characterise the clinical presentation of chronic chilblains in children.

METHODS:
This is a single-centre retrospective study of patients referred to our paediatric rheumatology clinic with cold, purple, and painful hands. Patients were identified from the paediatric rheumatology clinic database, at the Safra Children Hospital, Israel. Data of the clinical presentation, physical findings, laboratoy investigations and the course of the disease were extracted from the patients' charts and analysed.

RESULTS:
A total of 33 patients (27 females, sex ratio 4.5:1) were identified. Patients age at presentation was 13.5±2.1, and disease duration was 2.0±1.0 winters. Patients presented with prolonged capillary refill time (100%) and abnormal modified Allen test (75.6%). Fingers swelling was the most common finding (81.8%), followed by proximal interphalangeal joint (PIPs) swelling (63.6%), skin ulceration (54.5%), and dry, irritated skin (45.5%). Nailfold capillary microscopy was normal in all patients. The only abnormal laboratory test was the test for anti-nuclear factor (ANA) in 25%.

CONCLUSIONS:
We report a large series of children with a unique symptomatology consisting in chronic chilblains.
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NewsBot · Apr 9, 2013

Perniosis in an Infant Treated with Topical Nitroglycerine
Prashant Verma, Archana Singal, Pravesh Yadav
Pediatric Dermatology; Early View

Treatment of perniosis with topical nitroglycerin ointment is reported in a 6-month-old boy.
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NewsBot · Dec 16, 2017

Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia
Kelly K. Park et al
Pediatric Dermatology 12 December 2017

A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.
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NewsBot · May 16, 2023

Design Study of Adjuvant Treatment and Prevention of Chilblain
in Children with Ginger
Xuecheng Dai
BIO Web of Conferences 59, 02005 (2023)

In rural areas of central and Western China, chilblain is a common seasonal skin disease among
local children. Its symptoms are mainly skin redness, itching, peeling and even ulceration, which has a
negative impact on children's body and psychology. Due to the lack of attention and scientific cognition on
the treatment and prevention of chilblain, children with chilblain are prone to serious symptoms and have a
high probability of recurrence. This study conducted field investigation and user visits, earnestly considered
the multiple needs and scientific basis of users. This study combined with the different characteristics of
treatment and prevention and redesigned the primary methods of chilblain disease treatment and the
acceptability of various schemes for children in the initial stage of chilblain prevention and treatment. Using
the local traditional methods and natural materials, this design tests and improves the treatment methods of
local ginger soup and ginger juice smearing. Through the test of children's preferences, the application
methods of ointment and the redesign of medicine bottles that can be accepted and used by children are added
in the traditional treatment stage, as to design and produce new forms and carriers for chilblain treatment for
children, more loved and accepted by children.
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Chilblains in Children

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Chilblains in Children

NewsBot The Admin that posts the news.

Admin2 Administrator Staff Member

Bug Well-Known Member

NewsBot The Admin that posts the news.

NewsBot The Admin that posts the news.

NewsBot The Admin that posts the news.

NewsBot The Admin that posts the news.

Chilblains and Leukaemia

Chilblains or covid toes?

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Chilblains and Covid-19 (Covid Toes)

Chilblains are the pain of my life right now

Nifedipine Vs Placebo For Treatment Of Chilblains

Topical glyceryl trinitrate vs. oral nifedipine for chilblains

Share This Page

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