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Performance enhancing drugs

Discussion in 'General Issues and Discussion Forum' started by scotfoot, Jul 12, 2018 at 9:55 AM.

  1. scotfoot

    scotfoot Active Member


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    Having done a bit of reading and theorizing about the role of connective tissue in the performance of skeletal muscle ( see link below ) I have begun to wonder if the advantages in sporting performance gained by illegally taking anabolic steroids are ever really lost .

    It is important to note that I am not talking here about medication prescribed by a physician but rather about self medication by athletes looking to improve performance .

    I suspect that large doses of steroids will not only prompt growth of skeletal muscle but also growth of the connective tissue matrices that allow muscle to function , and that this expansion of the connective tissue framework within muscle persists for many years after the illegal use of the drugs has ceased . So after 2 years the contracticle component of the muscle may return to a more normal volume but the framework necessary for the optimal functioning of hypertrophied muscle may persist .

    Any thoughts ?

    Link
    Hydraulically discrete fascicles in skeletal muscle | Podiatry Arena

    https://podiatryarena.com › Forums › General › Biomechanics, Sports and Foot orthosesIf the perimysium is sufficiently impermeable then might it be possible that each fascicle is able to function as a hydraulically discrete unit with little or no ...
     
  2. scotfoot

    scotfoot Active Member

    With regard to the above , research has shown that the long term, illegal , misuse of high doses of anabolic steroids can lead to heart failure . In part this can be due to impaired diastolic function, which means that the left ventricle does not fill properly with blood during atrial contraction leading to reduced output from the ventricle when it, in turn , contracts .

    Could steroid abuse cause an increase in the connective tissue component of the cardiac muscle in the wall of the left ventricle effectively turning it into a hard to fill , hollow rubber ball ?

    My understanding is that heart problems caused by steroid abuse can manifest themselves long after abuse has ceased and hence my initial post in this thread.

    If connective tissue growth occurs in heart muscle in response to steroid abuse and if this persists over a long period post abuse , then perhaps the same is true of skeletal muscle .
     
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