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Gait pattern and lower extremity alignment in children with Morquio syndrome

Discussion in 'Pediatrics' started by NewsBot, Oct 2, 2012.

  1. NewsBot

    NewsBot The Admin that posts the news.

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    Gait pattern and lower extremity alignment in children with Morquio syndrome
    Dhawale, Arjun A.; Church, Chris; Henley, John; Holmes, Laurens Jr; Thacker, Mihir M.; Mackenzie, William G.; Miller, Freeman
    Journal of Pediatric Orthopaedics B: 22 September 2012
     
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    NewsBot The Admin that posts the news.

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    Morquio syndrome

    Morquio syndrome, also known as mucopolysaccharidosis type IV (MPS IV), is a rare metabolic disorder in which the body cannot process certain types of sugar molecules called glycosaminoglycans (AKA GAGs, or mucopolysaccharides). In Morquio syndrome, the specific GAG which builds up in the body is called keratan sulfate. This birth defect, which is autosomal recessive, is a type of lysosomal storage disorder. The buildup of GAGs in different parts of the body causes symptoms in many different organ systems.[2]: 544  In the US, the incidence rate for Morquio syndrome is estimated at between 1 in 200,000 and 1 in 300,000 live births.[1][3]

    1. ^ a b "MPS IV (Morquio syndrome)". MPSSociety.org. National MPS Society. Archived from the original on 21 August 2017. Retrieved 14 January 2015.
    2. ^ James, William D.; Berger, Timothy G. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
    3. ^ Prat C, Lemaire O, Bret J, Zabraniecki L, Fournié B (May 2008). "Morquio syndrome: Diagnosis in an adult". Joint Bone Spine. 75 (4): 495–8. doi:10.1016/j.jbspin.2007.07.021. PMID 18456538.
     
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