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hemochromatosis..Podiatric implications

Discussion in 'General Issues and Discussion Forum' started by footdrcb, Mar 2, 2011.

  1. footdrcb

    footdrcb Active Member


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    Hello all and sundry . A patient of mine has been diagnosed with H . She asked me what I knew about it and my answer was basically nothing as far as a podiatrist is concerned...

    She has balance problems, vertigo and is very tired all the time.

    Could anyone shed some light on this for me ..

    Kind regards and looking forward to your help

    FDCB

    :empathy:
     
  2. Admin2

    Admin2 Administrator Staff Member

    Iron overload

    Iron overload or haemochromatosis (also spelled hemochromatosis in American English) indicates increased total accumulation of iron in the body from any cause and resulting organ damage.[1] The most important causes are hereditary haemochromatosis (HH or HHC), a genetic disorder, and transfusional iron overload, which can result from repeated blood transfusions.[2]

    1. ^ Hsu CC, Senussi NH, Fertrin KY, Kowdley KV (June 2022). "Iron overload disorders". Hepatol Commun. 6 (8): 1842–1854. doi:10.1002/hep4.2012. PMC 9315134. PMID 35699322.
    2. ^ Hider RC, Kong X (2013). "Iron: Effect of Overload and Deficiency". In Astrid Sigel, Helmut Sigel and Roland K. O. Sigel (ed.). Interrelations between Essential Metal Ions and Human Diseases. Metal Ions in Life Sciences. Vol. 13. Springer. pp. 229–294. doi:10.1007/978-94-007-7500-8_8. ISBN 978-94-007-7499-5. PMID 24470094.
     
  3. Ninja11

    Ninja11 Active Member

    Hi Veteran.
    There is a link between patients with haemachromatosis, and therefore a predisposition to diabetes and gouty arthritis. The later inparticular seems to run in accordance with haemachromatosis, and from my limited experience with people diagnoses with these, the younger they are detected with haemachromatosis, the more gout throughout the body.
    A collegue has asked me to do a Case Study on my experience with this. Do you think it would be worthwhile?
    Cheers,
    Ninja11
     
  4. Ninja is this question directed to me - Mike will do fine if so

    Seems like a good idea Craig the thread stater asked if there was any related conditions. I had no idea but a quick search showed that secondary to the condition 2 very important Podiatry related conditions occur DM and Gout.

    So making more people aware of this with a published case study would be a good thing.

    Good luck let us know when and where we can read your paper.
     
  5. Blarney

    Blarney Active Member

    I had a patient today that presented with bilateral achilles pain of six months duration.

    She had a leaflet from her hospital clinic where she has just had her diagnosis of hemochromatosis confirmed - but they haven't started treatment as yet - saying that achilles problems may be as a result of her condition.

    Does anyone have advice or have seen similar presentation?

    Thanks

    Justin

    podiatry.ie
     
  6. This is a condition that I have more than a passing interest in. Not aware of complications such as gouty arthritis or DM - but depending on the iron deposition in the tissues at diagnosis, there can be many other complications - with the liver, heart and lungs bring the primary organs affected. Not heard of complications in muscle or connective tissue and would be surprised if the tendonosis occurred directly as a result.
     
  7. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Overview of Ankle Arthropathy in Hereditary Hemochromatosis
    Sara Calori et al
    Med Sci (Basel). 2023 Aug 15;11(3):51
     
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