Glucosamine and diabetes control?

Sean Millar · Apr 11, 2005

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Does glucosamine affect BSL's? Some research I have done (contacting manufactures of glucosamine), suggests it may reduce uptake of glucose at a cellular level. Nothing in MIMS. Patient this morning believed she could not take it because it upset her BSL's.
any feedback

Craig Payne · Apr 11, 2005

Glucosamine doesn't hurt blood glucose control
Will taking glucosamine chondroitin raise blood sugar levels?
Does Glucosamine Affect Blood Sugar Levels?

Sean Millar · Apr 11, 2005

glucosamine

that answers that question.
thank you craig

NewsBot · Oct 26, 2007

I know this is an old thread, but this just appeared:
The Effect of Glucosamine on Serum HDL Cholesterol and Apolipoprotein AI Levels in People With Diabetes
Stewart G. Albert, Rachel Fishman Oiknine, Shant Parseghian, Arshag D. Mooradian, Michael J. Haas, and Timothy McPherson
Diabetes Care 30:2800-2803, 2007

OBJECTIVE—Dietary and nutritional supplements are modulators of HDL cholesterol levels and production of apolipoprotein (apo) AI. Previously, in vitro treatment of hepatocyte cell lines with glucosamine increased apoAI production by stabilization of apoAI mRNA. The hypothesis is that the neutraceutical glucosamine, when given in conventional doses (1,500 mg/day) may increase apoAI and HDL cholesterol levels in subjects with diabetes and low HDL cholesterol.

RESEARCH DESIGN AND METHODS—Twelve subjects (three men and nine women) with type 1 (n = 2) and type 2 (n = 10) diabetes, aged 55 ± 12 years (mean ± SD), who had low HDL cholesterol (1.03 ± 0.20 mmol/l), were randomly assigned to a double-blind, placebo-controlled, cross-over trial of 500 mg glucosamine or placebo orally three times daily for 2 weeks, followed by a 4-week washout phase and a 2-week cross-over to the alternate therapy.

RESULTS—Fasting serum glucose, fructosamine, and total cholesterol remained stable during the drug and placebo phases. Glucosamine had no significant effect after therapy on serum levels of HDL cholesterol (from baseline of 1.02 ± 0.15 to 1.05 ± 0.16 mmol/l compared with placebo from 1.04 ± 0.21 to 1.06 ± 0.16 mmol/l) nor in changes in apoAI levels (from baseline of 147 ± 15 to 140 ± 126 mg/dl with glucosamine and from 146 ± 25 to 142 ± 17 mg/dl with placebo).

CONCLUSIONS—These observations suggest that glucosamine at commonly consumed doses does not have significant effects on glycemic control, lipid profile, or levels of apoAI in diabetic subjects after 2 weeks of supplementation.
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Glucosamine and diabetes control?

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Glucosamine and diabetes control?

Sean Millar Active Member

Craig Payne Moderator

Sean Millar Active Member

NewsBot The Admin that posts the news.

glucosamine sulfate

Glucosamine

Glucosamine

Glucosamine and rheumatoid arthritis

Glucosamine In Treatment Of Plantar Fasciitis

Glucosamine / Chondroitin in Osteoarthritis - the definitive study

New cancers in type 2 diabetes with diabetic foot disease

Share This Page

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