Moisturiser increasing INR?

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Hi everyone,

I just saw a 66 y old male patient today who has been using Foot Smart cream for his anhydrotic feet. Hx of DM, Hypertension and Burgers Disease. He is on Warfarin and recent blood tests results had shown INR of 4.8 since he started using Foot Smart. The patient and the wife have ruled out the other factors that may increase the INR and Foot Smart was the only thing they have changed. They have contacted the pharmaceutical company and they could not explain why the cream increases the INR. The main ingredients inlcude Urea, Allantoin, Sodium PCA and Vitamin E. The patient felt better when he was using the cream.
What would increase the INR from these ingredients? And any alternatives that i could suggest that are supplied in Australia?

Thanks

Aldrin C

 

Coincidence. I think the link would be described as tenuous at best...

It is much more likely that variation in diet, alcohol intake, medication interactions and the like are responsible. This is very well known and appreciated.

If there has been no recent change in medication profiles, LFTs etc, I would initially suggest the patient is increasing their INR due to reducing their vitamin K intake from changes in consumption of relevant vegetables, rather than topical application of cream.

LL

 

I Have to agree with the previous coments by Luckylisfranc. The INR is not set in stone so therefore this will fluctuate for the reasons stated.
coincidence I would also suggest