Welcome to the Podiatry Arena forums

You are currently viewing our podiatry forum as a guest which gives you limited access to view all podiatry discussions and access our other features. By joining our free global community of Podiatrists and other interested foot health care professionals you will have access to post podiatry topics (answer and ask questions), communicate privately with other members, upload content, view attachments, receive a weekly email update of new discussions, access other special features. Registered users do not get displayed the advertisements in posted messages. Registration is fast, simple and absolutely free so please, join our global Podiatry community today!

  1. Everything that you are ever going to want to know about running shoes: Running Shoes Boot Camp Online, for taking it to the next level? See here for more.
    Dismiss Notice
  2. Have you considered the Critical Thinking and Skeptical Boot Camp, for taking it to the next level? See here for more.
    Dismiss Notice
  3. Have you considered the Clinical Biomechanics Boot Camp Online, for taking it to the next level? See here for more.
    Dismiss Notice
Dismiss Notice
Have you considered the Clinical Biomechanics Boot Camp Online, for taking it to the next level? See here for more.
Dismiss Notice
Have you liked us on Facebook to get our updates? Please do. Click here for our Facebook page.
Dismiss Notice
Do you get the weekly newsletter that Podiatry Arena sends out to update everybody? If not, click here to organise this.

Phantom limb sensation explained

Discussion in 'General Issues and Discussion Forum' started by NewsBot, Feb 21, 2019.

  1. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1

    Members do not see these Ads. Sign Up.
    PUBLIC RELEASE: 21-FEB-2019
    Phantom limb sensation explained
    New study reveals functional changes among sensitive and motor brain areas after limb amputation, shedding light on the mechanisms behind the false idea that the limb is still present.


    After a limb amputation, brain areas responsible for movement and sensation alter their functional communication. This is the conclusion of a new study published today in Scientific Reports. According to the authors, from the D'Or Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ), the findings may help to understand why some patients report phantom sensations and others do not.

    Entitled "Lower limb amputees undergo long-distance plasticity in sensorimotor functional connectivity", the study represents a step forward a complete comprehension of a phenomenon called brain plasticity, which means the brain's ability to change itself in response to daily life situations. This ability is greater during the early stages of development but is still critical for learning, memory and behavior throughout our whole life. Investigating the underpinnings of brain plasticity is the key to develop new treatments against mental disorders.

    In order to go deeper on that, neuroscientists from Brazil decided to investigate the brain after lower limb amputation. In a previous study from the group, a magnetic resonance imaging experiment revealed that the brain overreacts when the stump is touched. Also, they found that the corpus callosum - brain structure that connects cortical areas responsible for movement and sensations - loses its strength. These findings have raised curiosity about what would be the impact of an impaired corpus callosum on the cortical areas it connects.

    Led by Fernanda Tovar-Moll, radiologist and president at IDOR, researchers investigated the differences in functional connectivity (i.e. the communication of brain areas) among motor and sensitive areas connected by the corpus callosum in nine lower limb amputees and nine healthy volunteers.

    The results showed that authors' idea was correct: in response to the touch in the stump, sensitive and motor areas of patients' brains exhibited an abnormal pattern of communication among the right and left hemispheres, probably as a consequence of impaired corpus callosum. In addition, sensitive and motor areas of the same hemisphere showed increased functional communication in amputees.

    "The brain changes in response to amputation have been investigated for years in those patients who report the phantom limb pain. However, our findings show that there is a functional imbalance even in the absence of pain, in patients reporting only phantom sensations", explains Ivanei Bramati, medical physicist and Ph.D. student at IDOR.

    According to the authors, understanding the changes of neural networks in response to the amputation can pave the way for the development of new technologies and devices to treat this disorder and offer patients a better quality of life.

    ###

    Reference

    Ivanei E. Bramati, Erika C. Rodrigues, Elington L. Simões, Bruno Melo, Sebastian Hoefle, Jorge Moll, Roberto Lent & Fernanda Tovar-Moll. Lower limb amputees undergolong-distance plasticity in sensorimotor functional connectivity. Scientific Reports, volume 9, Article number: 2518 (2019).
     
  2. Admin2

    Admin2 Administrator Staff Member

Loading...

Share This Page