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Tendinosis and antibiotics

Discussion in 'Biomechanics, Sports and Foot orthoses' started by Ian Drakard, Jun 21, 2011.

  1. Ian Drakard

    Ian Drakard Active Member


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    Hi all

    I'm aware of the link between tendinosis and ciprofloxacin.

    Does anyone know of any other antibiotics that can contribute to this, specifically lymecycline?

    Thanks in advance
     
  2. Ian Drakard

    Ian Drakard Active Member

    Or if anyone has a access to a copy of this paper?

    Acta Orthop. 2009 Dec;80(6):693-703.
    Metalloproteinases and their inhibitors-diagnostic and therapeutic opportunities in orthopedics.
    Pasternak B, Aspenberg P.
     
  3. Ian Drakard

    Ian Drakard Active Member

    Found a copy now
     
  4. Ian Drakard

    Ian Drakard Active Member

    Thanks Mike

    I think ciprofloxacin is one of the Fluoroquinolone class and is certainly worth being aware of.

    A current patient has been on pulsed lymecycline (a tetracyline group AB) for 12 plus years for Rosacea.

    It looks like tetracylines certainly have some effects on MMPs and I'm wondering if such a long period on this is contributing to her achilles tendinosis.

    http://informahealthcare.com/doi/pdfplus/10.3109/17453670903448257
     
  5. Ian Drakard

    Ian Drakard Active Member

    Good cross posting :drinks
     
  6. Can´t even begin to have any idea Ian sorry good luck . let us know what you find out.

    Love a good bit of cross posting :D
     
  7. drsarbes

    drsarbes Well-Known Member

    I have recently seen two partially ruptured achilles attributed to Levaquin.

    Steve
     
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