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Hi,

I have just begun a treatment plan for a patient with a longstanding VP - several options have failed such as OTC, Marigold Therapy, Silver Nitrate.

We have decided on Cryo,

What are peoples opinions on this method of treatment?
Any advise on application techniques or frequency - I was hoping for a 2-3 week interval?

Obviously Liquid Nitrogen is the most effective - or is it? What do others know about products such as Cryospray 59?

Thanks in advance

 

A very well respected lecturer in dermatology says that these canister type cryo products are next to useless as they do get down to lethal temp! The big cylinders do but can be very painful. The success rates of VP treatments aren't that great anyway!

Needling is probably the best!

 

Thanks,

Needling is a technique that I have never used or seen done but it is something I want to do - do you know of any courses or practitioners in/around Warwickshire that could help?

 

Hi Blue123,

The latest systematic reviews revealed very little high quality evidence for efficacy of VP tx. The 2012 Cochrane evaluated 85 RCT`s and determined that many were high risk of bias in design. On SalA & Cryo they found;

Salicylic acid (SA)- Definite but modest beneficial effect compared to placebo but may take several weeks of daily use to work.
Cryotherapy (liquid nitrogen) – Painful with risk of scarring. One study suggested cryo is better than SA for warts on the hands, but not evident when combined with other results.

They concluded; Studies were poor quality and best evidence suggests caustics, otherwise leave to allow natural resolution

Another review by Lipke stated;
– 52% Effectiveness Salicylic Acid
– 54% Effectiveness Cryotherapy

Occlusion, whether that be through Marigold therapy or duct tape and silver nitrate are no more effective than placebo.

The aim of all HPV tx is to promote a controlled and appropriate Immune Response, which exposes viral particles to antigen presenting cells. Theoretically, this can be acheived with any tx which creates a localised immune response to destruction of keratinocytes, that is trauma, whether that be via an acid or cold burn.

If you`re prepared to travel to Winchester, you are welcome to observe some needling. PM me.

Cheers,
Bel

 

My success rate with Cryospray are 60-80%, but I do a long freeze,thaw, freeze cycle.
I've also had some great success with needling since doing it this past year.
My clinic is in Warwickshire so please get in touch if you want to find out more.

 

What does Needling involve exactly?
Also I loved this
"The aim of all HPV tx is to promote a controlled and appropriate Immune Response, which exposes viral particles to antigen presenting cells. Theoretically, this can be acheived with any tx which creates a localised immune response to destruction of keratinocytes, that is trauma, whether that be via an acid or cold burn"

What about a hot burn?
Also how much do people charge for Liquid Nitro Is it a one off payment?
Or is it pay per session?
I am sure there is no money back guarantee if the wart is still there after Tx.

 

I recognise a fellow disciple demonstrating the ability to get what ya want without trying. True slack style, why bother to perform your own critical reviews or research when someone else can hand ya all the answers on a platter?

Praise Connie!

 

I am sure that we have been around this stump before; for my 1/2penny, I used hyfrecation or nothing. Based upon zero science, I found it to be essentially effective. But that was until I decided that routine wart treatment was not an ethical way forward. That was 1979. I accept totally the need for the odd-one treatment, but a routine treatment is not part of my vocab. Rob