Orthoses and Proteus Syndrome

Andrew · Mar 18, 2006

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I have a 28 year old male patient with Proteus Sydrome. He gets activity-related metatarsalgia and generalised foot pain.

Photos of his lower extremities are available here: <http://www.perthfootankle.com.au/proteus/>. As can be seen from these, he has quite a bit of excess soft tissue.

Any advice on what sort of orthoses might be helpful to him would be gratefully received. He has custom footwear in good condition.

Cheers, Andrew

Simon Spooner · Mar 18, 2006

I'd go for a weightbearing /semiweigthbearing full contact blown foam device.

Admin2 · Mar 18, 2006

For thise unfamiliar with Proteus Syndrome, there is the: Proteus Syndrome Foundation and this artilce from eMedicine: Proteus Syndrome

NewsBot · Aug 11, 2020

Proteus syndrome of the foot: A case report and literature review
Min He et al
Exp Ther Med. 2020 Sep;20(3):2716-2720

Proteus syndrome (PS) is an extremely rare and sporadic disorder characterized by asymmetric and/or disproportionate overgrowth of limbs, hamartomas, and vascular malformations. The onset of overgrowth usually involves the skin, bone, fat, and other connective tissues in a patchy or mosaic pattern. Partial gigantism of the affected limb or digit is a pathognomonic sign of PS. Thus far, only a few cases of PS have been recorded in the literature. In the present report, a case of PS in a 35-year old woman with classic cerebriform plantar hyperplasia and macrodactyly of the left foot was documented. The clinical and molecular characteristics and differential diagnosis of PS are also discussed in this report.
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