SUMMARY OF THE INVENTION
[0029] Accordingly, the present invention preferably seeks to mitigate, alleviate or eliminate one or more of the above-identified deficiencies in the art and disadvantages singly or in any combination and solves, among others, at least the problems mentioned above, by providing a device, a manufacturing method for the latter and a use of nitric oxide according to the appended patent claims.
[0030] According to one aspect of the invention, a device is provided that allows for target treatment of infections, caused by dermatophytes, yeast fungus, and mould fungus, such as onychomycosis and dermatophytosis. The device comprises a nitric oxide (NO) eluting polymer arranged to contact the infected area, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area.
[0031] According to another aspect of the invention, a manufacturing process for such a device is provided, wherein the process is a process for forming a device that allows for target treatment of infections, caused by dermatophytes, yeast fungus, and mould fungus, such as onychomycosis and dermatophytosis. The process comprises selecting a plurality of nitric oxide eluting polymeric particles, such as nanofibers, fibers, nanoparticles, or microspheres and deploying said nitric oxide eluting particles in a condom/sheath or tape/coating to be comprised in said device. Alternatively the NO eluting particles are admixed to an ointment, cream, gel or foam.
[0032] The present invention has at least the advantage over the prior art that it provides target exposure of an infected area to NO, whereby a very effective anti-dermatophyte, anti-yeast fungus, and/or anti-mould fungus therapy is achievable.
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