Gait in Spinal Muscular Atrophy

NewsBot · Nov 20, 2016

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Gait Assessment with SoleSound Instrumented Footwear in Spinal Muscular Atrophy.
Montes Jet al
Muscle Nerve. 2016 Nov 18. doi: 10.1002/mus.25484.

BACKGROUND:
Gait impairment is common in spinal muscular atrophy (SMA) and is described using clinical assessments and instrumented walkways. Continuous over-ground walking has not been studied.
METHODS:
Nine SMA participants completed the six-minute walk test (6MWT) and 10-meter walk/run wearing instrumented footwear (SoleSound). Data were simultaneously collected using a reference system (GAITRiteTM ). The root mean square error (RMSE) indicated criterion validity. The decrease in walking speed represented fatigue. Foot loading patterns were evaluated using force sensors.
RESULTS:
The RMSE for stride time, length, and velocity ranged from 1.3-1.7%. Fatigue was 11.6±9.1%, which corresponded to an average deceleration of 0.37±0.28mm/s2 . Participants spent most of stance without heel contact. Forefoot contact occurred early in the gait cycle.
CONCLUSIONS:
These results suggest that footwear-based devices are an alternative to specialized equipment for gait assessment. Better understanding of gait disturbances should inform ongoing treatment efforts and provide a more sensitive outcome measure.
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