Hypophosphatemia and heel pain

NewsBot · Nov 3, 2010

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Familial hypophosphatemia: an unusual presentation with low back ache, heel pain, and a limp in a young man, and literature review.
Arthur S, Chopra A.
Clin Rheumatol. 2010 Nov 2. [Epub ahead of print]

A case of young man with low back ache and heel pains who was examined in a rheumatology outpatient and diagnosed as familial hypophosphatemia (FH), probably X-linked (XL), is presented. FH is most commonly transmitted as XL. The role of PHEX gene and fibroblast growth factor 23 is also described.
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NewsBot · Oct 6, 2023

This clinical trial was just registered:
Foot Disorders in X-linked Hypophosphatemia

This study aimed to characterize foot pathologies using X-rays and clinical examination and assess related outcome scores in adolescents and adults with X-linked Hypophophatemia
Detailed Description
A single center, cross-sectional analysis of adolescent and adult patients with XLH with and without previous surgical intervention was performed at the Orthopaedic Hospital Speising, Vienna, Austria. Patients with confirmed XLH, ≥ 16 years were invited to participate in this study. Exclusion criteria were other forms of hypophosphatemia, pregnancy and recent lower limb surgery within 3 months. The study was approved by a local ethics committee (EK37/2020). During a period of one year (07/20 to 07/21), data of 28 patients with XLH were available for this study. Two adults were excluded due to pregnancy. Radiographic data of a total of 26 adolescents and adults with XLH (51 legs) and clinical data of a total 37 limbs were included into this study. One foot was excluded from analysis due to recent surgical intervention at the knee. The study cohort overlaps with the study population of Akta et al. (2).
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