Metatarsalgia in Morquio A Syndrome (Mucopolysaccharidosis type IV)

NewsBot · May 7, 2020

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Metatarsalgia in Morquio A Syndrome
Mohammad M Eid, Mohammed K Al-Safi, Sager S Hanna and Aliaa
Khaja
Acta Scientific Clinical Case Reports 1.3 (2020): 18-23

Morquio A Syndrome, also known as Mucopolysaccharidosis type IV (MPS IV), is a lysosomal storage disease of autosomal recessive pattern. The disease is rare and features musculoskeletal and cardiopulmonary complications. We present a case study of
Morquio A Syndrome with pes planus and metatarsus elevatus. The patient had a long history of metatarsalgia and a severe antalgic
gait. Upon investigation, it was discovered that the deformity was caused by ligamentous deforming forces of the foot, linked to
ligamentous restrictions seen in Morquio A Syndrome. An overload of the metatarsal heads leads to subsequent 1st metatarsal base
subluxation and 2nd and 3rd rigid hammer toes. Surgical correction was done by a Lapidus procedure and simultaneous correction
of the metatarsus elevatus deformity of the 1st ray, as well as a flexor hallucis longus transfer to the extensor hallucis longus. The
procedure was successful in terms of pain relief and return of functional level.
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