Rectal colonization is a risk factor for mortality in patients with diabetic foot infections

NewsBot · Apr 28, 2015

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KPC-producing Klebsiella pneumoniae rectal colonization is a risk factor for mortality in patients with diabetic foot infections
Carlo Tascini, Benjamin A. Lipsky, Elisabetta Iacopi, Andrea Ripoli, Francesco Sbrana, Alberto Coppelli, Chiara Goretti, Alberto Piaggesi, Francesco Menichetti
Clinical Microbiology and InfectionAvailable online 22 April 2015

To evaluate the relationship between KPC-Kp gut colonization and mortality in diabetic patients with foot infection (DFI) we performed a single-center, retrospective, matched case-control study. In the study period, we identified 21 DFI patients with KPC-Kp gut colonization and 21 controls. The 90 day mortality rate was significantly higher in gut colonized patients (47%) than the controls (4%) (p= 0.013). A multivariate analysis demonstrated that gut colonization with KPC-Kp was the only independent predictor of mortality (odds ratio [CI]= 13.33 [1.90, 272.80], p= 0.024). In patients with DFI, KPC-Kp gut colonization appears to be an important risk factor for mortality.
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Admin2 · Apr 28, 2015

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