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Resveratrol

Polyphenol with a stilbene skeleton

Chemical compound

Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi.^[6][7] Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries, and peanuts.^[8][9]

Although commonly used as a dietary supplement and studied in laboratory models of human diseases,^[10] there is no high-quality evidence that resveratrol improves lifespan or has a substantial effect on any human disease.^[11][12]

1. ^ ^{a b} Camont, Laurent; Cottart, Charles-Henry; Rhayem, Yara; et al. (February 2009). "Simple spectrophotometric assessment of the trans-/cis-resveratrol ratio in aqueous solutions". Anal. Chim. Acta. 634 (1): 121–128. Bibcode:2009AcAC..634..121C. doi:10.1016/j.aca.2008.12.003. PMID 19154820.
2. ^ ^{a b} "Resveratrol MSDS on Fisher Scientific website". Archived from the original on 2012-11-03. Retrieved 2012-03-06.
3. ^ Resveratrol MSDS on www.sigmaaldrich.com
4. ^ Bechmann LP, Zahn D, Gieseler RK, et al. (June 2009). "Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells". Hepatology Research. 39 (6): 601–608. doi:10.1111/j.1872-034X.2008.00485.x. PMC 2893585. PMID 19207580.
5. ^ GHS: Sigma-Aldrich R5010
6. ^ "Resveratrol". Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR. 11 June 2015. Retrieved 26 August 2019.
7. ^ Fremont, Lucie (January 2000). "Biological Effects of Resveratrol". Life Sciences. 66 (8): 663–673. doi:10.1016/S0024-3205(99)00410-5. PMID 10680575.
8. ^ Jasiński M, Jasińska L, Ogrodowczyk M (August 2013). "Resveratrol in prostate diseases – a short review". Central European Journal of Urology. 66 (2): 144–149. doi:10.5173/ceju.2013.02.art8. PMC 3936154. PMID 24579014.
9. ^ Cite error: The named reference pe was invoked but never defined (see the help page).
10. ^ "Resveratrol". MedlinePlus. 1 April 2019. Retrieved 22 September 2019.
11. ^ Cite error: The named reference pmid21698226 was invoked but never defined (see the help page).
12. ^ Sahebkar A, Serban C, Ursoniu S, et al. (2015). "Lack of efficacy of resveratrol on C-reactive protein and selected cardiovascular risk factors – Results from a systematic review and meta-analysis of randomized controlled trials". International Journal of Cardiology. 189: 47–55. doi:10.1016/j.ijcard.2015.04.008. PMID 25885871.

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