Found the following article fascinating: The Certainty of Uncertainty in Medicine (Medscape article - hence you need to log-in). It is somewhat related to this other recent thread: Accuracy of medical press releases (which has a more press/news exaggeration perspective)... whilst the article of this thread has a more research perspective...
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Fascinating topic... unfortunately, it's not just medicine which has suffered the above traits i.e. areas relating to Biology have also suffered (but best leave that apparent thorn alone).
I would assume that Podiatry is faring quite well (from my experience)... however, there are other fields i.e. Chiropractic, which have had their inquiries (at least within Australia) of which haven't fared so well.
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Here is that John Ioannidis paper cited in the previous post:
Why Most Published Research Findings Are False (apparently... "it has become the most accessed article in the history of the Public Library of Science, known as PLOS")...
Another (more recent i.e. 2014) John Ioannidis paper on a related issue:
How to Make More Published Research True...
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Excellent Matt - the two best posts you've written to date!
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I should qualify the last post by saying I enjoy reading your contributions, Matt. It just takes a while!
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As another saying goes... "all good things take time" ;) -
There is also a fantastic book on this topic called Doctoring Data
http://www.doctoringdata.co.uk/
It makes for very interesting reading -
Another fascinating article recently published in relation to this topic/thread... reducing/assessing the processes that may lead scientists to stop fooling themselves (& subsequently others) i.e. elimination of "motivated reasoning" & "confirmation bias" :
The Trouble With Scientists (http://nautil.us/issue/24/error/the-trouble-with-scientists)...
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I've been sitting on this article for a while... it's just a news article... but have revisited it today & the content is still interesting (for this thread). It discusses similar issues to what has been discussed above (i.e. poor science research/interpretation of data). The reason I've been sitting on it is that I don't want to be seen as someone knocking "science"... I love science... but it disturbs me when I see science abuse or science misconduct... particularly when it is deliberate. Podiatry Arena has discussed quite a number of papers which has been tainted with the likes of poor science research/interpretation of data... particularly within the field of biomechanics (i.e. barefoot, footwear, orthotic related topics).
William Reville: Something has gone very wrong with science (http://www.irishtimes.com/news/scie...ng-has-gone-very-wrong-with-science-1.2245846)
Problems of which may include the following (views of Richard Horton, editor-in-chief of the Lancet)...
Retraction Watch (http://retractionwatch.com/). A blog that reports on the retractions of scientific papers (science misconduct etc...), such as...
High-profile biologist is suspended after two investigations found he “breached his duty of care”, committed “misconduct” ...
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Reminds me that when other Podiatrists refute my findings in a pilot study on growing pains, simply because I did not use a placebo orthotic, (the efficacy which has been challenged here at PA), it begs the question about what we really are interested in...better patient outcomes or ego?
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This article found in QUARTZ:
Many scientific "truths" are, in fact, false (http://qz.com/638059/many-scientific-truths-are-in-fact-false/)
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Yes, drowning in data overload (& what to believe). Interesting, albeit frustrating trends within scientific/medical research (i.e. cherry picking data to suit one's agenda)…
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