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Critical limb ischemia

Discussion in 'Diabetic Foot & Wound Management' started by NewsBot, Oct 12, 2012.

  1. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Press Release:
    Loss of protective heart failure protein linked to critical limb ischemia
    S100A1 could be a potential therapeutic target in critical limb ischemiato promote revascularization, say Thomas Jefferson University researchers from the Center for Translational Medicine
     
  2. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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    Press Release:
    Covidien Announces Final Results from Landmark DEFINITIVE LE Study in Patients with Peripheral Arterial Disease
     
  3. Admin2

    Admin2 Administrator Staff Member

  4. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Outcomes of angiosome and non-angiosome targeted revascularization in critical lower limb ischemia.
    Kabra A, Suresh KR, Vivekanand V, Vishnu M, Sumanth R, Nekkanti M.
    J Vasc Surg. 2012 Oct 8.
     
  5. Selwyn Firth

    Selwyn Firth Member

    I have found 4 abstracts of articles proving that increasing circulation using a pneumatic compression device increase wound healing amongst diabetic patients.
    The links are
    http://1.usa.gov/19bas8
    http://1.usa.gov/ndrMLV
    http://1.usa.gov/QX4At9
    http://1.usa.gov/WAerJi.

    It seems that since circulation is a major factor in wound healing then any device which increases it should have a similar effect. There is but one battery powered portable device on the market and it has shown some remarkable success so far.

    If anyone wishes to find out more they can find me on twitter.

    Selwyn Firth
     
  6. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Endovascular Revascularization for Patients with Critical Limb Ischemia: Impact on Wound Healing and Long Term Clinical Results in 189 Limbs.
    Bae JI, Won JH, Han SH, Lim SH, Hong YS, Kim JY, Kim JD, Kim JS.
    Korean J Radiol. 2013 May;14(3):430-438.
     
  7. Selwyn Firth

    Selwyn Firth Member

    If the protein is so effective, it might be quicker and more effective to just make copies and give injections similar to insulin for the treatment of Type 1 diabetes. Cost of gene therapy may be too expensive and not cost effective based on expected extension of lifetimes.The researchers should try making and using the protein before moving into gene therapy.
     
  8. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Press Release:
    Procedures saving limbs of more peripheral arterial disease patients, Mayo Clinic finds
    Amputation study among several being presented at Society for Vascular Surgery conference
     
  9. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Growing Impact of Restenosis on the Surgical Treatment of Peripheral Arterial Disease
    Douglas W. Jones, MD; Andres Schanzer, MD; Yuanyuan Zhao, MA; Todd A. MacKenzie, PhD; Brian W. Nolan, MD; Michael S. Conte, MD; Philip P. Goodney, MD, MS, The Vascular Study Group of New England
    J Am Heart Assoc. 2013; 2: e000345
     
  10. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Our treatment strategy for critical limb ischemia.
    Yamada T, Onishi K, Utsunomiya M, Nakamura M.
    Int J Vasc Med. 2013;2013:437471. doi: 10.1155/2013/437471.
     
  11. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Peripheral Arterial Testing Before Lower Extremity Amputation Among Medicare Beneficiaries, 2000 to 2010.
    Vemulapalli S, Greiner MA, Jones WS, Patel MR, Hernandez AF, Curtis LH.
    Circ Cardiovasc Qual Outcomes. 2014 Jan 14
     
  12. Admin2

    Admin2 Administrator Staff Member

    Multidisciplinary approach to treatment of patients with lower limb critical ischaemia.
    Maksimov AV, Koreĭba KA, Nuretdinov RM, Usmanov MA, Glinkin VV.
    Angiol Sosud Khir. 2013;19(4):122-126.
     
  13. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
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  14. NewsBot

    NewsBot The Admin that posts the news.

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    Press Release:
    THE SAGE GROUP LLC Announces Publication of an Article Titled “Cost-Benefit Analysis of Amputation in the Era of the Affordable Care Act. Is it Fiscally Responsible to Perform Primary Amputation as Treatment?” in the May Issue of Endovascular Today
     
  15. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Urgent endovascular revascularization in acute on chronic critical limb ischemia.
    Troisi N, Ercolini L, Chisci E, Barbanti E, Peretti E, Setti M, Pitì A, Michelagnoli S.
    J Cardiovasc Surg (Torino). 2014 Sep 12.
     
  16. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Great Toe Necrosis Predicts an Unfavorable Limb Salvage Prognosis.
    Sano, Hitomi MD, PhD; Ichioka, Shigeru MD, PhD
    Plastic and Reconstructive Surgery; September 22, 2014
     
  17. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    A systematic review of intermittent pneumatic compression for critical limb ischaemia.
    Moran PS, Teljeur C, Harrington P, Ryan M.
    Vasc Med. 2014 Sep 30.
     
  18. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    An early validation of the Society for Vascular Surgery Lower Extremity Threatened Limb Classification System.
    Cull DL, Manos G, Hartley MC, Taylor SM, Langan EM, Eidt JF, Johnson BL.
    J Vasc Surg. 2014 Oct 1
     
  19. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Evaluation and Treatment of Patients With Lower Extremity Peripheral Artery Disease: Consensus Definitions From Peripheral Academic Research Consortium (PARC).
    Patel MR et al
    J Am Coll Cardiol. 2015 Mar 10;65(9):931-941. doi: 10.1016/j.jacc.2014.12.036.
     
  20. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Predictors of Delayed Wound Healing after Endovascular Therapy of Isolated Infrapopliteal Lesions Underlying Critical Limb Ischemia in Patients with High Prevalence of Diabetes Mellitus and Hemodialysis.
    Shiraki T et al
    Eur J Vasc Endovasc Surg. 2015 Mar 3
     
  21. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Press Release:
    Lower extremity revascularization not effective in majority of nursing home residents
    UCSF researchers find most patients still alive gain little, if any, function

     
  22. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Prognosis of critical limb ischemia: Minor vs major amputation comparison.
    Matsuzaki K et al
    Wound Repair Regen. 2015 Jun 17
     
  23. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Outcomes of One straight-line flow with and without pedal arch in patients with critical limb ischemia.
    Higashimori A et al
    Catheter Cardiovasc Interv. 2015 Oct 22
     
  24. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Functional Imaging of the Foot with Perfusion Angiography in Critical Limb Ischemia.
    Reekers JA et al
    Cardiovasc Intervent Radiol. 2015 Dec 1
     
  25. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Below-the-Knee Angioplasty for Critical Limb Ischemia: Results of a series of 157 procedures and impact of the Angiosome Concept
    Marie Pave et al
    Annals of Vascular Surgery; 15 July 2016
     
  26. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Determining End Points for Critical Limb Ischemia Interventions.
    Cooper KJ, Pe?a C, Benenati J
    Tech Vasc Interv Radiol. 2016 Jun;19(2):104-112. doi: 10.1053/j.tvir.2016.04.003. Epub 2016 Apr 22.
     
  27. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Lumbar sympathectomy techniques for critical lower limb ischaemia due to non-reconstructable peripheral arterial disease.
    Karanth VK, Karanth TK, Karanth L.
    Cochrane Database Syst Rev. 2016 Dec 13;12:CD01151
     
  28. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Risk Factors for Mortality Among Individuals With Peripheral Arterial Disease
    S.M. Amrock, C.Z. Abraham, E. Jung, P.B. Morris, M.D. Shapiro
    Am J Cardiol 2017;120:862-7.
     
  29. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Recurrence of Critical Limb Ischemia After Endovascular Intervention in Patients with Diabetic Foot Ulcers.
    Meloni M et al
    Adv Wound Care (New Rochelle). 2018 Jun 1;7(6):171-176. doi: 10.1089/wound.2017.0778.
     
  30. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    The impact of foot infection on infrainguinal bypass outcomes in patients with chronic limb-threatening ischemia.
    Mayor JM et al
    Vasc Surg. 2018 Jul 28. pii: S0741-5214(18)31068-1
     
  31. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Clinical characteristics of Japanese diabetic patients with critical limb ischemia presenting Fontaine stage IV
    Mitsuyoshi TakaharaOsamu IidaYukihiro FujitaMasakazu Haneda
    Diabetology International: 08 December 2018
     
  32. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    A Review and Proposed Classification System for the No-Option Patient With Chronic Limb-Threatening Ischemia
    Tanner I. Kim, MD, Shant S. Vartanian, MD, Peter A. Schneider, MD
    Journal of Endovascular Therapy October 9, 2020
     
  33. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Research priorities for lower limb amputation in patients with vascular disease
    DC Bosanquet et al
    Source
     
  34. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Continuous peripheral nerve block for in-patients with lower limb ischemic pain
    Hermann Dos Santos Fernandes et al
    Clinics (Sao Paulo). 2021;76:e2805
     
  35. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Hospital Payer Mix and Amputation Rates Among Patients with Peripheral Artery Disease Complications
    Deeksha Bidare, Neal R Barshes
    Ann Vasc Surg. 2022 Apr 25
     
  36. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Management of the no-option foot: Deep vein arterialization
    Sadia Ilyas, Richard J Powell
    Semin Vasc Surg. 2022 Jun;35(2):210-218
     
  37. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Press release:
    Insights from largest chronic limb-threatening ischemia study to inform quality of care improvements
    Data from a cohort of one million patients with chronic limb-threatening ischemia (CLTI) were presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions. Using data from Medicare, the cohort, Chronic Limb threatening Ischemia Process PERformance (CLIPPER), found one out of six patients with CLTI died within their first year of diagnosis and 50% survived at five years.

    CLTI is a serious condition in which blood flow to the feet or legs is severely limited by atherosclerotic plaque. Patients with CLTI are at high risk of lower extremity amputation and death without prompt diagnosis and treatment. Though CLTI is common and highly morbid, there are no established process measures to guide high-quality care. Using data from Medicare, the CLIPPER cohort was created to develop and test process measures for CLTI, which could ultimately be used to measure and improve quality of care.

    Using inpatient and outpatient claims data from patients with fee-for-service Medicare from 2010 to 2019, a coding algorithm was used to identify patients with CLTI. To qualify for a CLTI diagnosis, patients had either 1) one diagnostic code for peripheral artery disease and one diagnostic code for ulceration, infection, or gangrene on the same inpatient or outpatient claim, or 2) one CLTI-specific diagnostic code, as well as a procedure code indicating arterial vascular testing within six months before or after the qualifying CLTI diagnostic code(s).

    The cohort comprised 1,130,065 patients diagnosed with CLTI between 2010 and 2019. Mean age of the cohort was 75 ± 5.8 years; 48.4% were women and 14.6% were Black. Within 30 days of CLTI diagnosis, 20.4% of patients underwent percutaneous or surgical revascularization. Within 6 months, 3.3% of patients underwent major amputation; 16.7% of patients died at 1-year follow-up and 50.3% at 5-year follow-up.

    “CLTI is an incredibly deadly disease if not treated quickly after diagnosis, but we know very little about how hospitals perform with respect to treatment,” said Alexander Fanaroff, MD, MHS and Assistant Professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania and lead author. “Comprehensive process measures are needed for patients in order to advance care and improve the chance of survival. Our hope is that this study is a first step toward developing better process measures.”
     
  38. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Lower extremity Allen test in critical limb ischemia
    Khurram H Khan et al
    Source
     
  39. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Hospital clinicians’ perceptions and experiences of care pathways for chronic limb-threatening ischaemia: a qualitative study
    Eleanor Atkins, Ian Kellar, Panagiota Birmpili, Jonathan R. Boyle, Arun D. Pherwani, Ian Chetter & David A. Cromwell
    Journal of Foot and Ankle Research volume 16, Article number: 62 (2023)
     
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