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Iontophoretic application of terbinafine to toenails

Discussion in 'General Issues and Discussion Forum' started by NewsBot, Oct 8, 2008.

  1. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1

    Members do not see these Ads. Sign Up.
    This clinical trial has just been registered:

    Iontophoretic Application of Terbinafine Gel to the Large Toe Nail
     
  2. Admin2

    Admin2 Administrator Staff Member

  3. a.mcmillan

    a.mcmillan Guest

    Wondering if they will have a control group / condition, with the gel applied without iontopheresis ? Otherwise the data cannot demonstrate the penetration levels of the drug due to the modality …

    The findings may also have greater external validity if subjects had dystrophic nails, rather than healthy….. and if clinical outcomes were used in addition to tissue concentration levels ?

    Interesting though …:rolleyes:
     
  4. Craig Payne

    Craig Payne Moderator

    Articles:
    6
    As they are using normal people and not assessing clinical outcomes, its just a Phase 2 study on the use of terbinafine this way ... begs the question as to why they bothered to register it ???
     
  5. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Transungual delivery of terbinafine by iontophoresis in onychomycotic nails.
    Nair AB, Vaka SR, Murthy SN.
    Drug Dev Ind Pharm. 2011 Oct;37(10):1253-8
     
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