Diabetic Foot Complications and Pancreas Transplantation

NewsBot · Mar 23, 2017

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Diabetic Foot Complications Despite Successful Pancreas Transplantation
Dong-Kyo Seo, MD, Ho Seong Lee, MD, PhD, Jungu Park, MD, Chang Hyun Ryu, MD, Duck Jong Han, MD, PhD, Sang Gyo Seo, MD
Foot & Ankle International

Background:
It is known that successful pancreas transplantation enables patients with diabetes to maintain a normal glucose level without insulin and reduces diabetes-related complications. However, we have little information about the foot-specific morbidity in patients who have undergone successful pancreas transplantation. The purpose of this study was to investigate the prevalence and predisposing factors for foot complications after successful pancreas transplantation.

Methods:
This retrospective study included 218 patients (91 males, 127 females) who had undergone pancreas transplantation for diabetes. The mean age was 40.7 (range, 15-76) years. Diabetes type, transplantation type, body mass index, and diabetes duration before transplantation were confirmed. After pancreas transplantation, the occurrence and duration of foot and ankle complications were assessed.

Results:
Twenty-two patients (10.1%) had diabetic foot complications. Fifteen patients (6.9%) had diabetic foot ulcer and 7 patients (3.2%) had Charcot arthropathy. Three patients had both diabetic foot ulcer and Charcot arthropathy. Three insufficiency fractures (1.4%) were included. Mean time of complications after transplantation was 18.5 (range, 2-77) months. Creatinine level 1 year after surgery was higher in the complication group rather than the noncomplication group (P = .02).

Conclusion:
Complications of the foot and ankle still occurred following pancreas transplantation in patients with diabetes.
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Admin2 · Mar 23, 2017

Related Topics:
Renal failure and foot ulcer or lower extremity amputation in those patients with diabetes
Foot ulceration and onset of renal dialysis

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