EMLA cream prior to verruca treatment

NewsBot · Jun 3, 2016

Members do not see these Ads. Sign Up.
A Double-Blind, Randomised, Placebo-Controlled Trial of EMLA Cream (Eutectic Lidocaine/Prilocaine Cream) for Analgesia Prior to Cryotherapy of Plantar Warts in Adults.
Lee SH, Pakdeethai J, Toh MP, Aw DC.
Ann Acad Med Singapore. 2014 Oct;43(10):511-4.

INTRODUCTION:
Cryotherapy with liquid nitrogen is an effective, safe and convenient form of treatment for plantar warts. EMLA cream (eutectic mixture of lidocaine 2.5% and prilocaine 2.5%) is a topical local anaesthetic agent that has proven to be effective and well tolerated in the relief of pain associated with various minor interventions in numerous clinical settings.
MATERIALS AND METHODS:
In a single-centre, double-blind, randomised placebo-controlled study, 64 subjects were randomised into 2 groups. The subjects had a thick layer of EMLA cream or placebo cream applied to pared plantar wart(s) and onto the surrounding margin of 1 mm to 2 mm under occlusion for 60 minutes prior to receiving cryotherapy. The pain of cryotherapy was evaluated by the subjects using a self-administered Visual Analogue Scale (VAS) immediately after the cryotherapy.
RESULTS:
There was no statistical difference between the mean VAS score for EMLA? cream (47.0 ? 21.4 mm) and placebo (48.9 ? 22.0 mm). Those with more than 1 wart had a significantly higher VAS score than those with only 1 wart (59.1 ? 21.8 vs. 44.3 ? 20.4, P <0.05) but this did not affect the therapeutic effect of EMLA? cream prior to cryotherapy.
CONCLUSION:
We conclude that the application of EMLA? cream prior to cryotherapy does not reduce the pain associated with cryotherapy.
Click to expand...

NewsBot The Admin that posts the news.

Multiple puncture technique using anaesthetic cream (emla)

EMLA cream improved sensation in diabetic neuropathy

EMLA cream and ulcer debridement

Emla crema

Improvement of Sensibility in the Foot in Diabetic Patients Induced by EMLA-application to the Lower

Efficacy of LL-37 cream in enhancing healing of diabetic foot ulcer

Lysine cream for diabetic foot ulcers

Share This Page