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    Effect of hyperbaric oxygen on cardiac neural regulation in diabetic individuals with foot complications.
    Diabet Med. 2006 Apr;23(4):360-6
     
  2. Admin2 Administrator Staff Member

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    Point and counterpoint

    Counterpoint: hyperbaric oxygen for diabetic foot wounds is not effective.
    Clin Infect Dis. 2006 Jul 15;43(2):193-8
    Author: Berendt AR
    Point: hyperbaric oxygen is beneficial for diabetic foot wounds.
    Clin Infect Dis. 2006 Jul 15;43(2):188-92
    Author: Barnes RC
     
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    Effects of hyperbaric oxygen therapy on circulating interleukin-8, nitric oxide, and insulin-like growth factors in patients with type 2 diabetes mellitus.
    Clin Biochem. 2006 Aug 14;
    Chen SJ, Yu CT, Cheng YL, Yu SY, Lo HC
     
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    Early and late effects of hyperbaric oxygen treatment on oxidative stress parameters in diabetic patients.
    Physiol Res. 2007 Jan 2;
    Gürdöl F, Cimşit M, Oner-Iyidogan Y, Körpinar S, Yalçinkaya S, Koçak H
     
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    Factors influencing the outcome of lower-extremity diabetic ulcers treated with hyperbaric oxygen therapy.
    Fife CE, Buyukcakir C, Otto G, Sheffield P, Love T, Warriner R
    Wound Repair Regen. 2007 May-Jun;15(3):322-31.
     
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    The clinical and economic potential of hyperbaric oxygen therapy in the treatment of diabetic ulceration and other conditions.
    McMillan G, Glover M.
    Int J Low Extrem Wounds. 2007 Sep;6(3):130-8.
     
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    Hyperbaric oxygen therapy in the management of diabetic lower limb wounds.
    Ong M.
    Singapore Med J. 2008 Feb;49(2):105-9.
     
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    Cost-effectiveness and budget impact of adjunctive hyperbaric oxygen therapy for diabetic foot ulcers.
    Chuck AW, Hailey D, Jacobs P, Perry DC.
    Int J Technol Assess Health Care. 2008 Spring;24(2):178-83
     
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    Can major amputation rates be decreased in diabetic foot ulcers with hyperbaric oxygen therapy?
    Kaya A, Aydin F, Altay T, Karapinar L, Ozturk H, Karakuzu C.
    Int Orthop. 2008 Jul 25. [Epub ahead of print]
     
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    Effect of Hyperbaric Oxygen Therapy on Healing of Diabetic Foot Ulcers.
    Duzgun AP, Satır HZ, Ozozan O, Saylam B, Kulah B, Coskun F.
    J Foot Ankle Surg. 2008 November - December;47(6):515-519.
     
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    Hyperbaric oxygen, oxidative stress, NO bioavailability and ulcer oxygenation in diabetic patients.
    Efrati S, Gall N, Bergan J, Fishlev G, Bass A, Berman S, Hamad-Abu R, Feigenzon M, Weissgarten J.
    Undersea Hyperb Med. 2009 Jan-Feb;36(1):1-12.
     
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    Hyperbaric oxygen therapy for wound healing and limb salvage: a systematic review.
    Goldman RJ.
    PM R. 2009 May;1(5):471-89.
     
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    Diabetic persons with foot ulcers and their perceptions of hyperbaric oxygen chamber therapy.
    Katarina H, Magnus L, Per K, Jan A.
    J Clin Nurs. 2009 Jul;18(14):1975-85.
     
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    A three species model to simulate application of Hyperbaric Oxygen Therapy to chronic wounds.
    Flegg JA, McElwain DL, Byrne HM, Turner IW.
    PLoS Comput Biol. 2009 Jul;5(7):e100045
     
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    Mathematical Model of Hyperbaric Oxygen Therapy Applied to Chronic Diabetic Wounds.
    Flegg JA, Byrne HM, McElwain DL.
    Bull Math Biol. 2010 Mar 5. [Epub ahead of print]
     
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    Hyperbaric Oxygen Therapy Facilitates Healing of Chronic Foot Ulcers in Patients With Diabetes
    Magnus Löndahl, Per Katzman, Anders Nilsson, and Christer Hammarlund
    Diabetes Care May 2010 vol. 33 no. 5 998-1003
     
  18. drwmmiller Member

    Although I treat a good number of Diabetic Wounds, in my experience I have not seen a dramatic effect on wound healing. The one indication I absolutely use it is of course with a wound etiology of PVD and patients post-op with gas gangrene. Perhaps I simply do not have enough experience with it as I admittedly lowered my usage of it after seeing minimal to no improvement in my first five attempt. However, I applaud the study:
    Diabet Med. 2006 Apr;23(4):360-6
    and will research it further.
     
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    Hyperbaric oxygen therapy and diabetic foot ulcers: Knowledge and attitudes of Canadian primary care physicians.
    Evans AW, Gill R, Valiulis AO, Lou W, Sosiak TS.
    Can Fam Physician. 2010 May;56(5):444-52.
     
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    Treatment of diabetic foot infection with hyperbaric oxygen therapy.
    Chen CE, Ko JY, Fong CY, Juhn RJ.
    Foot Ankle Surg. 2010 Jun;16(2):91-95.
     
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    Potential benefits of hyperbaric oxygen therapy on atherosclerosis and glycaemic control in patients with diabetic foot.
    Karadurmus N, Sahin M, Tasci C, Naharci I, Ozturk C, Ilbasmis S, Dulkadir Z, Sen A, Saglam K.
    Endokrynol Pol. 2010;61(3):275-279.
     
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    Relationship between ulcer healing after hyperbaric oxygen therapy and transcutaneous oximetry, toe blood pressure and ankle-brachial index in patients with diabetes and chronic foot ulcers.
    Löndahl M, Katzman P, Hammarlund C, Nilsson A, Landin-Olsson M.
    Diabetologia. 2010 Oct 19. [Epub ahead of print]
     
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    Relationship between ulcer healing after hyperbaric oxygen therapy and transcutaneous oximetry, toe blood pressure and ankle–brachial index in patients with diabetes and chronic foot ulcers
    M. Löndahl, P. Katzman, C. Hammarlund, A. Nilsson and M. Landin-Olsson
    Diabetologia Volume 54, Number 1, 65-68, 2010
     
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    Hyperbaric oxygen therapy improves health-related quality of life in patients with diabetes and chronic foot ulcer
    Magnus Löndahl, Mona Landin-Olsson, Per Katzman
    Diabetic Medicine (in press)
     
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    Hyperbaric oxygen therapy improves health-related quality of life in patients with diabetes and chronic foot ulcer.
    Löndahl M, Landin-Olsson M, Katzman P.
    Diabet Med. 2011 Feb;28(2):186-90.
     
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    A prospective, double-blind, randomized, controlled clinical trial comparing standard wound care with adjunctive Hyperbaric Oxygen Therapy (HBOT) to standard wound care only for the treatment of chronic, non-healing ulcers of the lower limb in patients with diabetes mellitus: a study protocol.
    O'Reilly DJ, Linden R, Fedorko L, Tarride JE, Giffening Jones W, Bowen JM, Goeree R.
    Trials. 2011 Mar 7;12(1):69. [Epub ahead of print]
     
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    What is the Role of Hyperbaric Oxygen in the Management of Diabetic Foot Disease?
    Löndahl M, Fagher K, Katzman P.
    Curr Diab Rep. 2011 May 3. [Epub ahead of print]
     
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    The Role of Hyperbaric Oxygen in the Treatment of Diabetic Foot Ulcers.
    Tiaka EK, Papanas N, Manolakis AC, Maltezos E.
    Angiology. 2011 Aug 25.
     
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    Hyperbaric oxygen therapy for chronic wounds.
    Kranke P, Bennett MH, Martyn-St James M, Schnabel A, Debus SE.
    Cochrane Database Syst Rev. 2012 Apr 18;4:CD004123.
     
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    From the 2012 ADA Mtg:
    Survival in Diabetic Foot Ulcer Patients After Hyperbaric Oxygen Therapy
    MAGNUS LÖNDAHL, CHRISTER HAMMARLUND, PER KATZMAN, Lund, Sweden, Helsingborg, Sweden
     
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    Diabetic foot ulcers treated with hyperbaric oxygen therapy: a review of the literature.
    Bishop AJ, Mudge E.
    Int Wound J. 2012 Jul 2.
     
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    Control groups in hyperbaric trials.
    Sherlock S.
    Diving Hyperb Med. 2012 Sep;42(3):183.
     
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    Wound healing: the evidence for hyperbaric oxygen therapy.
    J Mills B.
    Br J Nurs. 2012 Nov 8-21;21(20):28-34.
     
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    Systematic Review of the Effectiveness of Hyperbaric Oxygenation Therapy in the Management of Chronic Diabetic Foot Ulcers
    Rui Liu, Ling Li, Mengliu Yang, Guenther Boden, Gangyi Yang
    Mayo Clinic Proceedings, Volume 88, Issue 2, Pages 166-175
     
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    Lack of Effectiveness of Hyperbaric Oxygen Therapy for the Treatment of Diabetic Foot Ulcer and the Prevention of Amputation
    A cohort study

    David J. Margolis, Jayanta Gupta, Ole Hoffstad, Maryte Papdopoulos, Henry A. Glick, Stephen R. Thom, Nandita Mitra
    Diabetes Care February 19, 2013
     
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    A prospective, randomized, controlled study of hyperbaric oxygen therapy: effects on healing and oxidative stress of ulcer tissue in patients with a diabetic foot ulcer.
    Ma L, Li P, Shi Z, Hou T, Chen X, Du J.
    Ostomy Wound Manage. 2013 Mar;59(3):18-24.
     
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  38. Paul Bowles Well-Known Member

    Latest research presented at DFCON 2013 states HBO is not successful. Full lecture available FREE on www.portaleducation.com under DFCON 2013 section. Unfortunately I can't post it here yet!
     
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    HYPER BARIC OXYGEN THERAPY VERSUS MONOCHROMATIC INFRARED THERAPY IN THE MANAGEMENT OF DIABETIC FOOT ULCER
    Safa S. Abdel Karim, Emad T. Ahmed
    INNOVATIVE JOURNAL OF MEDICAL AND HEALTH SCIENCE Vol 3, No 3 (2013)
     
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    Hyperbaric oxygen therapy for diabetic ulcers: systematic review and meta-analysis.
    O'Reilly D, Pasricha A, Campbell K, Burke N, Assasi N, Bowen JM, Tarride JE, Goeree R.
    Int J Technol Assess Health Care. 2013 Jul;29(3):269-81.
     
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