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Oxybutynin for plantar hyperhidrosis

Discussion in 'General Issues and Discussion Forum' started by NewsBot, Feb 16, 2014.

  1. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1

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    Randomized trial - oxybutynin for treatment of persistent plantar hyperhidrosis in women after sympathectomy
    Altair da Silva Costa Jr, Luiz Eduardo Villaça Leão, José Ernesto Succi, Joao Aléssio Juliano Perfeito, Adauto Castelo Filho, Erika Rymkiewicz, Marco Aurelio Marchetti Filho
    Clinics vol.69 no.2 São Paulo Feb. 2014
     
  2. Admin2

    Admin2 Administrator Staff Member

  3. Admin2

    Admin2 Administrator Staff Member

    Oxybutynin

    Oxybutynin (brand names Ditropan, Lyrinel XL, Lenditro (ZA), Driptane (RU), Uripan (Middle East)[1]) is an anticholinergic medication used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder.[2] Also given to help with symptoms associated with kidney stones.

    It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. It also has direct spasmolytic effects on bladder smooth muscle as a calcium antagonist and local anesthetic, but at concentrations far above those used clinically.

    Oxybutynin is also a possible treatment of hyperhidrosis (hyperactive sweating).[3][4][5]

    1. ^ "Uripan Tablets". Adwia Pharmaceuticals. Retrieved 22 November 2015. 
    2. ^ Chapple CR. "Muscarinic receptor antagonists in the treatment of overactive bladder". Urology (55)5, Supp. 1:33-46, 2000.
    3. ^ Tupker RA, Harmsze AM, Deneer VH (2006). "Oxybutynin therapy for generalized hyperhidrosis.". Arch Dermatol. 142 (8): 1065–6. doi:10.1001/archderm.142.8.1065. PMID 16924061. 
    4. ^ Mijnhout GS, Kloosterman H, Simsek S, Strack van Schijndel RJ, Netelenbos JC (2006). "Oxybutynin: dry days for patients with hyperhidrosis.". Neth J Med. 64 (9): 326–8. PMID 17057269. 
    5. ^ Schollhammer M, Misery L (2007). "Treatment of hyperhidrosis with oxybutynin.". Arch Dermatol. 143 (4): 544–5. doi:10.1001/archderm.143.4.544. PMID 17438194. 
     
  4. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Long-Term Efficacy of Oxybutynin for Palmar and Plantar Hyperhidrosis in Children Younger than 14 Years
    Nelson Wolosker et al
    Pediatric Dermatology; Early View
     
  5. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Long-term results of the use of oxybutynin for the treatment of plantar hyperhidrosis
    Nelson Wolosker et al
    International Journal of Dermatology; Early View
     
  6. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Oxybutynin as a treatment for generalized hyperhidrosis: a randomized, placebo-controlled trial
    M. Schollhammer et al
    British Journal of Dermatology; Accepted Article
     
  7. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Initial study of transdermal oxybutynin for treating hyperhidrosis
    José Francisco Millán-Cayetano, et al
    The Journal of Dermatology
     
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