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Blame your parents for bunion woes

Discussion in 'General Issues and Discussion Forum' started by NewsBot, May 20, 2013.

  1. NewsBot

    NewsBot The Admin that posts the news.


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    Press Release
    Blame your parents for bunion woes
    Common foot deformities are inherited says framingham foot study
  2. Admin2

    Admin2 Administrator Staff Member

  3. NewsBot

    NewsBot The Admin that posts the news.

    Hallux valgus and lesser toe deformities are highly heritable in adult men and women: The Framingham foot study
    Marian T. Hannan, Hylton B. Menz, Joanne M. Jordan, L. Adrienne Cupples, Chia-Ho Cheng, Yi-Hsiang Hsu
    Arthritis Care & Research Early View
  4. Nope. Google "heritability hallux valgus". At least one of the authors was definitely aware of my PhD since he requested a copy some years ago. I sent a copy to one of his PhD students, who went on to ask a couple of questions regarding it. I can probably find the correspondence if necessary. Anyway, as you will see from your google search the top hit, my PhD thesis is now freely available via the gift of the t'interweb and has been so for a number of years. If you read the details of the link at the top of your google search you'll see that my PhD has also been cited 4 times. I'm pretty sure there has also been a study since which reported similar heritability estimates to the ones which I reported, hence I find it strange that the authors proclaim to be the first to perform such a study, to the best of their knowledge. Never mind.
  5. drsha

    drsha Banned

    Interesting Simon:

    Have you ever researched what excactly precurses the part or portion of the inheritability of these families to bunions, etc.

    Could it be an inherited nature of >>>>>>>???

    possibly you could list your top 5.

    I'll list my top 5.

    Inherited biomechanical foot type
    Inherited genotypes for collagen, bone and other connective tissue
    Inherited MBI
    Inherited musculoskeletal strength and weakness
    Inherited socioeconomic scenario

  6. I suggest your read my thesis, Dennis.
  7. drsha

    drsha Banned

    I would be honored.

    Perhaps you can offer a link.

  8. Griff

    Griff Moderator


    STEVE LEVITZ Active Member


    STEVE LEVITZ Active Member

    I am familiar with ALL of the unshode articles on HAV
    I had been an avid reader of AJPA and studied at The American Museum of Natural History 1974-5
    The sparse articles on unshod HAV are few and there is a confusion between HAV and congenital Hallux Interphalangeous in many articles.
  11. I only studied this topic for my PhD.

    STEVE LEVITZ Active Member

    Click here: paleopathology of hav ajpa 2005

    STEVE LEVITZ Active Member

    Please re read Philip hoffman fro 1905
  14. Please read.

    STEVE LEVITZ Active Member

    I would say we are not in agreement
  16. Rob Kidd

    Rob Kidd Well-Known Member

    It is many years since I read it, Simon, but the issue I had at the time was the old thorny one - cause of, or caused by? That is, was the met angle you spent so much time with the cause od the HAV, or was it caused by HAV? As a side issue, I spent some time in the mid 90's working on squatting facets and found this to be a serious issue. Bone morphology is transient, at least in the context of squatting.

    Outside the thesis, is there any further work on this?

  17. blinda

    blinda MVP

    Last edited: May 28, 2013
  18. wdd

    wdd Well-Known Member

    Blame your parents for bunion woes only if you are white and of European descent. Everyone else breath a sigh of relief or wait with bated breath.


  19. Indeed. See: http://archive.samj.org.za/1980 VOL...HREE SOUTH AFRICAN POPULATIONS. F.A.B. Go.pdf

    All subjects in the above study were habitually shod, yet clear difference existed in the prevalence of hallux valgus by race. Perhaps there were "racial" differences in the footwear?

    There are a number of studies which show a prevalence of hallux valgus in habitually barefoot populations, for example see Maclennen 1966 http://www.lancet.com/journals/lancet/article/PIIS0140-6736(66)90304-7/fulltext
    While the prevalence reported within such studies is generally lower (Maclennen reported 4 % of his female subjects displayed hallux valgus) shoes could have played no role in the development of the deformity within these un-shod subjects. While congenital hallux valgus is even rarer, it is reported within the literature too.

    We now have two pretty large studies showing a significant genetic component to hallux valgus. However, neither of these studies reported that hallux valgus was 100% genetic, i.e. there is an environmental component. I have little doubt that footwear accounts for part of that environmental component; but to say that hallux valgus is caused by footwear per se is naive.

    There are also a couple of studies which have attempted pedigree analysis, reporting autosomal dominant with reduced penetrance.

    Rob, I think you may have my study confused with another, I was not interested in causality with regard to the metatarsus primus varus component.
  20. wdd

    wdd Well-Known Member

    Just an aside but does anyone know how big the world's habitually unshod population is? I would imagine that it's shrinking fast and probably for the same type of reason that the Framingham foot study only looked at a white population of European descent.

    Apparently the Framingham project started in 1948 with a cohort consisting of a randomly selected 2/3 of the population in the town of Framingham MA. At that time the town must have been almost or exclusively inhabited by whites of European ancestry. It seems that they have now recruited inhabitants from the non-white section of the population although they just seem to have lumped them together. However the Framingham Foot Studies, it seems, are based on the original population and their children and grandchildren. I wonder if they actively screened out the children of interracial couples?


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