Essential Oils for Diabetic Foot Ulcers

NewsBot · Feb 2, 2018

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The Wound Healing Effects of Herbal Cream
Containing Oliveria Decumbens and Pelargonium
Graveolens Essential Oils in Diabetic Foot Ulcer Model
Mohaddese Mahboubi et al
http://wjps.ir/article-1-302-en.pdf

BACKGROUND
The number of diabetic patients in adult population is increasing.
All this population are at risk of developing diabetic foot ulcers
(DFUs) that are associated with unwanted ailments and high
mortality. In spite of current therapies for DFUs, further therapies
are needed to help the patients.
METHODS
The efficacy of herbal cream containing Pelargonium graveolens and
Oliveria decombens essential oils was evaluated topically for treatment
of DFUs in rat animal model in comparison with two other herbal
formulas containing each essential oil alone, placebo (the basic formula
without active ingredients) and normal saline as control groups. After
anesthesia of diabetic rats (n=75) induced by streptozotocin (STZ),
diabetic wounds were visible on the hind dorsal surface of the foot.
The treatments were initiated on Day 1 and repeated 3 times in a day
for thirteen consecutive days. On day 1, 3, 5, 8 and 13, the wound sizes
were determined and assessed histologically.
RESULTS
Three herbal formulations reduced the size of wounds in rats
with DFUs, while the cream containing combined herbals of O.
decumbens and P. graveolens essential oils had the highest tissue
repair in DFU rat models.
CONCLUSION
Due to better wound healing effects of combined herbal cream
containing O. decumbens and P. graveolens essential oils, it can
be recommended in treatment of DFUs.
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Admin2 · Feb 2, 2018

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