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New invention could revolutionize the way wounds are treated

Discussion in 'Diabetic Foot & Wound Management' started by admin, Dec 1, 2004.

  1. admin

    admin Administrator Staff Member


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    New invention could revolutionize the way wounds are treated

    From WYKC.com
     
  2. sodakpod

    sodakpod Welcome New Poster

    this looks nice, any experience

    This looks very promising, what experience does anyone have using it?
     
  3. docgary

    docgary Welcome New Poster

    that dog won't hunt

    Sorry guys - but surrounding external oxygen around a wound will not do ANYTHING with regards to increasing oxygen to the cell! The ONLY benefit may be in treating a strict anaerobe infection as done years ago.

    Even administering oxygen via nasal cannula or mask cannot increase the concentration of o2 to the wound since the hemoglobin molecule in the RBC can only carry a finite amout of oxygen to the cells.

    The only way you can increase the partial pressure of oxygen in cells (as transcutaneous partial pressure of oxygen (Tcpo2) as measured by TCOMs -transcutaneous oxygen measurements (TCOM) is utilizing HYPERBARIC OXYGEN THERAPY

    Having briefly worked with HBOT and lower extremity wounds, the improvement noted both by anectodal and statistical evidence is overwhelming.

    Any portable external oxygen device is, IMHO, a gimmick.

    Dr Gary Friedman
     
  4. Dawn Bacon

    Dawn Bacon Active Member

    Some 20+ years ago directing a current of oxygen over the surface of recalcitrant wounds was considered beneficial. However since the practice failed to produce improved outcomes it was relatively short lived.
     
  5. docgary

    docgary Welcome New Poster

    "...the practice failed to produce improved outcomes..."
    because the tissue was unaffected by the application of oxygen.
    If you look into the archives, external application of 02 was utilized
    for anaerobic infection adjunct Tx. :eek:
     
  6. Dawn Bacon

    Dawn Bacon Active Member

    Hi Gary,

    "because the tissue was unaffected by the application of oxygen.
    If you look into the archives, external application of 02 was utilized
    for anaerobic infection adjunct Tx."

    Quite so. However not all of us need to look into the archives, some had first hand experience of the rationale for and the application of topical oxygen (I was one of the poor students who had the unenviable task of directing said oxygen over the surface of seemingly unending wounds :( ).
     
    Last edited: Sep 30, 2005
  7. C Bain

    C Bain Active Member

    Google Trawl!

    Hi All,

    Just a comment, an interesting trawl through Google.

    1. Go to Google.

    2. Put in Wounds Oxygen (1,310,000 entries!).

    The difference in the new and the 20yrs. back approach is that oxygen I believe was blown across the wounds originally. Today continues oxygen is fed into the dressing. Big difference in the application of the oxygen! It was only available in the US. a year or so ago when I tried to find the applicator??? (Anybody?).

    Regards,

    Colin.

    PS. A sudden thought? Should the Patient be warned not to stand to close to an open flame or strike a match whilst wearing the device?
     
    Last edited: Oct 1, 2005
  8. C Bain

    C Bain Active Member

    Topical Oxygen for Chronic Wounds!

    Hi All,

    I have just come across an abstract on,

    UHMS position statement: topical oxygen for chronic wounds.

    Medical College of Ohio USA.

    Worth a read!

    www.woundupdate.com/ Found in Chronic/Impaired Wounds Screen for September 2005.

    Regards,

    Colin.
     
  9. sodakpod

    sodakpod Welcome New Poster

    Response to Medical College of Ohio Post

    The product in this post is not like the "topical" sleeves being referred to in the article you mentioned. Within the original post of this thread it says this new device is "transdermal", not "topical" like being mentioned in the Ohio position statement.
     
  10. sodakpod

    sodakpod Welcome New Poster

  11. David Smith

    David Smith Well-Known Member

    DR Gary

    Might it be possible that occluding sunlight and flushing with O2 might reduce localized ground level ozone which may inhibit healing Ref; Toxicol Lett. 2005 Aug 26; Modulation of cutaneous wound healing by ozone: Differences between young and aged mice.
    Lim Y, Phung AD, Corbacho AM, Aung HH, Maioli E, Reznick AZ, Cross CE, Davis PA, Valacchi G. Department of Internal Medicine, School of Medicine, UC Davis, Davis CA, USA. PMID: 16129572 PubMed
    So might it be possible that flushing an occluded wound with any gas may have the same effect?

    Cheers Dave Smith
     
  12. rwr104

    rwr104 Welcome New Poster

    I am a little confused by the terminology - Transdermal suggests one thing to me but the info from the company (http://www.ogenix.net/overview.htm) states "to blanket the wound". So this IS a topical application, which is being labeled Transdermal.
     
  13. bizgoz

    bizgoz Welcome New Poster

    Hi All,

    I work for the company that makes this device and though they are old, your criticisms are 100% inaccurate. We have over 79% efficacy in treating ONLY the most recalcitrant wounds, all over 6 months old. These are wounds that have failed all other widely accepted treatments including HBOT, NWPT, and standard of care. In the last 18 months, EPIFLO has completely healed 14 wounds that were already scheduled for amputation. Because of skepticisim like the above, we only get the worst of the worst cases. Since this was written, we have over 200 case studies, with the vast majority proving this therapy is extremely effective. Any professional who sees chronic wounds that won't heal or heal very slow who is in denial of this treatment is doing a huge disservice to their patients. Our biggest advocates as well as our opinion leaders were skeptics themselves at one time. Email me if you would like names.

    At present it is only reimbursable through the VA and prisons. We have begun 120 patient multi site RCT with several of the most respected wound care facilities and physicians in the US and Canada. You will recogize their names.

    There is a paper by Dr. Sen of Ohio State which shows that topical oxygen DOES work. Note that our product is different than topical because it works 24/7 instead of 3 x 90 minute weekly sessions. Our RCT includes studies into the mechanism of oxygen as well.

    Here are some pages with info you may find useful:

    http://ogenix.com/home/page/sitemap
    http://ogenix.com/home/page/clinical
    http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2565554


    I can email you more...not everything has yet been published. We also recently received our CE mark, though we are not currently selling in Europe.

    Email info@ogenix.com or post here if you want all to see.
     
    Last edited by a moderator: Jun 8, 2009
  14. pgcarter

    pgcarter Well-Known Member

    I seem to remember from Uni Training that the pathologists were saying that access to O2 and Zinc had a rate determining influence on the function of fibroblasts? if that is true then 24/7 topical O2 may be of some use, if it's true that the early trials were only 90 min in 24hr and that this new thing is 24/7 we are not comparing apples with apples. I hope the future results show a benefit.
    regards Phill
     
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