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Oxybutynin for plantar hyperhidrosis

Discussion in 'General Issues and Discussion Forum' started by NewsBot, Feb 16, 2014.

  1. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1

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    Randomized trial - oxybutynin for treatment of persistent plantar hyperhidrosis in women after sympathectomy
    Altair da Silva Costa Jr, Luiz Eduardo Villaça Leão, José Ernesto Succi, Joao Aléssio Juliano Perfeito, Adauto Castelo Filho, Erika Rymkiewicz, Marco Aurelio Marchetti Filho
    Clinics vol.69 no.2 São Paulo Feb. 2014
     
  2. Admin2

    Admin2 Administrator Staff Member

  3. Admin2

    Admin2 Administrator Staff Member

    Oxybutynin

    Oxybutynin, sold as under the brand names Ditropan among others, is a medication used to treat overactive bladder.[1] It works similar to tolterodine.[1] While used for bed wetting in children, evidence to support this use is poor.[1] It is taken by mouth or applied to the skin.[1]

    Common side effects include dry mouth, dizziness, constipation, trouble sleeping, and urinary tract infections.[1] Serious side effects may include urinary retention and an increased risk of heat stroke.[1] Use in pregnancy appears safe but has not been well studied while use in breastfeeding is of unclear safety.[2] It is an antimuscarinic and works by blocking the effects of acetylcholine on smooth muscle.[1]

    Oxybutynin was approved for medical use in the United States in 1975.[1] It is available as a generic medication.[3] A month supply in the United Kingdom costs the NHS less than GB£3 per month as of 2019.[3] In the United States the wholesale cost of this amount is about US$14.[4] In 2016 it was the 108th most prescribed medication in the United States with more than 6 million prescriptions.[5]

    1. ^ a b c d e f g h "Oxybutynin Chloride Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 3 March 2019.
    2. ^ "Oxybutynin Pregnancy and Breastfeeding Warnings". Drugs.com. Retrieved 3 March 2019.
    3. ^ a b British National Formulary: BNF 76 (76th ed.). Pharmaceutical Press. 2018. ISBN 9780857113382.
    4. ^ "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services. Retrieved 3 March 2019.
    5. ^ "The Top 300 of 2019". clincalc.com. Retrieved 22 December 2018.
     
  4. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Long-Term Efficacy of Oxybutynin for Palmar and Plantar Hyperhidrosis in Children Younger than 14 Years
    Nelson Wolosker et al
    Pediatric Dermatology; Early View
     
  5. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Long-term results of the use of oxybutynin for the treatment of plantar hyperhidrosis
    Nelson Wolosker et al
    International Journal of Dermatology; Early View
     
  6. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Oxybutynin as a treatment for generalized hyperhidrosis: a randomized, placebo-controlled trial
    M. Schollhammer et al
    British Journal of Dermatology; Accepted Article
     
  7. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Initial study of transdermal oxybutynin for treating hyperhidrosis
    José Francisco Millán-Cayetano, et al
    The Journal of Dermatology
     
  8. NewsBot

    NewsBot The Admin that posts the news.

    Articles:
    1
    Oxybutynin as an alternative treatment for hyperhidrosis
    Sergio Delort et al
    An. Bras. Dermatol. vol.92 no.2 Rio de Janeiro Mar./Apr. 2017
     
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