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Painful Diabetic Neuropathy Guidelines Released

Discussion in 'Diabetic Foot & Wound Management' started by NewsBot, Apr 12, 2011.

  1. NewsBot

    NewsBot The Admin that posts the news.

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    Evidence-based guideline: Treatment of painful diabetic neuropathy
    Report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation
    V. Bril et al
    Neurology (Published online before print April 11)
     
  2. NewsBot

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    Press Release:
    AAN Issues New Guideline on Best Treatments for Diabetic Nerve Pain
     
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  4. NewsBot

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    Topical Ketamine Cream in the Treatment of Painful Diabetic Neuropathy
    A Randomized, Placebo-controlled, Double-blind Initial Study

    James M. Mahoney, Vassilios Vardaxis, Joshua L. Moore, Andrew M. Hall, Kyle E. Haffner, Matthew C. Peterson
    J Am Podiatr Med Assoc 102(3): 178–183, 2012
     
  5. NewsBot

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    Randomized control trial of topical clonidine for treatment of painful diabetic neuropathy.
    Campbell CM, Kipnes MS, Stouch BC, Brady KL, Kelly M, Schmidt WK, Petersen KL, Rowbotham MC, Campbell JN.
    Pain. 2012 Jun 8
     
  6. NewsBot

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    Randomized, Placebo-Controlled Comparison of Amitriptyline, Duloxetine, and Pregabalin in Patients With Chronic Diabetic Peripheral Neuropathic Pain
    Impact on pain, polysomnographic sleep, daytime functioning, and quality of life

    Julia Boyle et al
    Diabetes Care September 18, 2012
     
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    From Guideline to Patient: A Review of Recent Recommendations for Pharmacotherapy of Painful Diabetic Neuropathy
    Dan Ziegleremail, Vivian Fonseca
    Journal of Diabetes and Its Complications; Articles in Press
     
  8. NewsBot

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    Prevalence of diabetic peripheral neuropathy in Iran: a systematic review and meta-analysis.
    Sobhani S, Asayesh H, Sharifi F, Djalalinia S, Baradaran HR, Arzaghi SM, Mansourian M, Rezapoor A, Ansari H, Masoud MP, Qorbani M.
    J Diabetes Metab Disord. 2014 Oct 15;13(1):97
     
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    Double-blind, placebo-controlled study of HGF gene therapy in diabetic neuropathy
    John A. Kessler, A. Gordon Smith, Bong-Soo Cha, Sung Hee Choi, James Wymer, Aziz Shaibani, Senda Ajroud-Driss and VM202 DPN-II Study Group†
    Annals of Clinical and Translational Neurology; Early View
     
  10. NewsBot

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    Systematic review of treatments for diabetic peripheral neuropathy
    N. ?akici et al
    Diabetic Medicine; Accepted Article
     
  11. NewsBot

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    Vitamin D for the treatment of painful diabetic neuropathy
    Abdul Basit et al
    BMJ Open Diab Res Care 2016;4:e000148
     
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    PUBLIC RELEASE: 12-DEC-2016
    New compound eases neuropathic pain from light touch
    Study in mice identifies an agent that tunes-down ion channel responsible for mechanical hypersensitivity
     
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    PUBLIC RELEASE: 12-DEC-2016
    Scientists discover how to reverse pain caused by diabetes-related nerve damage
     
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    A Cross-Sectional Web Survey of Satisfaction with Treatment for Pain in Participants with Suspected Diabetic Peripheral Neuropathic Pain in Both Feet
    Takahisa Deguchi et al
    Adv Ther. 2021 Jul 8
     
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    Systemic inflammatory biomarkers in painful diabetic neuropathy
    PanoraiaBakaFabiolaEscolano-LozanoFrankBirklein
    Journal of Diabetes and its Complications; Volume 35, Issue 10, October 2021, 108017
     
  17. NewsBot

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    Press Release:
    AAN issues guideline for treatment of painful diabetic neuropathy


    Diabetic neuropathy refers to nerve damage due to diabetes and it may lead to pain and numbness, most often in the hands and feet. To help neurologists and other doctors determine the best treatment for people with diabetic neuropathy, the American Academy of Neurology (AAN) has issued a guideline Neurology®, the medical journal of the AAN, and is endorsed by the American Association of Neuromuscular & Electrodiagnostic Medicine. This guideline updates the 2011 AAN guideline on the treatment of painful diabetic neuropathy.
    “Living with pain can greatly affect a person’s quality of life, so this guideline aims to help neurologists and other doctors provide the highest quality patient care based on the latest evidence,” said guideline author Brian C. Callaghan, MD, MS, of the University of Michigan in Ann Arbor and a Fellow of the American Academy of Neurology. “Painful diabetic neuropathy is very common, so people with diabetes who have nerve pain should discuss it with their doctor because treatment may help.”
    The guideline states that there are many oral and topical medications that are effective in reducing nerve pain. Before prescribing a treatment, it says a doctor should first determine if a person also has mood or sleep problems since treatment for these conditions is also important.
    To reduce nerve pain, the guideline recommends that doctors may offer treatments from the following drug classes: tricyclic antidepressants (TCAs) such as amitriptyline, nortriptyline and imipramine; serotonin-norepinephrine reuptake inhibitors (SNRIs) such as duloxetine, venlafaxine or desvenlafaxine; gabapentinoids such as gabapentin or pregabalin; and/or sodium channel blockers such as carbamazepine, oxcarbazepine, lamotrigine, or lacosamide. Evidence shows these medications may all reduce nerve pain.
    “New studies on sodium channel blockers published since the last guideline have resulted in these drugs now being recommended and considered as effective at providing pain relief as the other drug classes recommended in this guideline,” said Callaghan.
    When prescribing, the guideline says doctors should consider the cost of a drug, side effects as well as other medical problems the person may have. Once taking a drug, people should be checked by their doctors to determine if there is enough pain relief or too many side effects.
    If the first medication tried does not provide meaningful improvement, or if there are significant side effects, the guideline states that doctors should offer patients a trial of another medication from a different class.
    The guideline states that opioids should not be considered for treatment.
    “Current evidence suggests that the risks of the use of opioids for painful diabetic neuropathy therapy outweigh the benefits, so they should not be prescribed,” said Callaghan.
    The guideline states that doctors may offer topical treatments such as capsaicin, glyceryl trinitrate spray orCitrullus colocynthis to reduce pain. It also says ginkgo biloba may be helpful, as well as non-drug treatments such as exercise, mindfulness, cognitive behavioral therapy or tai chi.
    “It is important to note that the recommended drugs and topical treatments in this guideline may not eliminate pain, but they have been shown to reduce pain,” said Callaghan. “The good news is there are many treatment options for painful diabetic neuropathy, so a treatment plan can be tailored specifically to each person living with this condition.”
    To further assist neurologists and other doctors with treating painful diabetic neuropathy, the AANhas also published a new AAN Polyneuropathy Quality Measurement Set to accompany this guideline. A quality measurement set is a tool doctors can use to improve the ways care is delivered to patients.
     
  18. NewsBot

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    An overview of painful diabetic peripheral neuropathy: diagnosis and treatment advancements
    Jonathan M. Hagedorn
    May 14, 2022 et al
     
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    Diagnosis, management and impact of painful diabetic peripheral neuropathy: A patient survey in four European countries
    Solomon Tesfaye et al
    Journal of Diabetes and its Complications; 10 February 2023, 108417
     
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    Where Art Thou O treatment for diabetic neuropathy: the sequel
    Yigit Can Guldiken et al
    Expert Rev Neurother. 2023 Aug 21;1-7
     
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