Topical haemoglobin for diabetic foot ulceration

NewsBot · Jun 26, 2015

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Topical haemoglobin spray for diabetic foot ulceration.
Bateman SD
Br J Nurs. 2015 Jun 24;24(Sup12):S24-S29.

The development and subsequent deterioration of diabetic foot ulceration (DFU) is a common occurrence across all healthcare divides, concerning all patient groups, age, gender and social environments. It increases demand on clinical resources and creates unnecessary hardship for patients. Chronic DFU is challenging to prevent and notoriously difficult to manage owing to the complex nature of the patient and the disease itself. The improvement of oxygenation to many chronic wound groups is gaining momentum across wound care; particularly in those wounds such as DFU that present with circulatory, oxygen-deficient scenarios.
METHOD:
A descriptive evaluation was undertaken in an acute clinical setting where a spray solution containing purified haemoglobin was used in a cohort of 20 patients who presented with chronic (>12 weeks) DFU. Standard wound care was undertaken by 18 health professionals with no changes to products, devices or practice before evaluation. All wounds received the addition of the product on eight set occasions over a 4-week period and the resulting data correlated in regards to the set outcomes of wound surface area reduction, ease of use, adverse events and patient acceptability.
RESULTS:
At 4 weeks all wounds had demonstrated positive wound reduction, there were no adverse events, all patients and clinicians found the product acceptable and easy to use. Interestingly, although not a set outcome, all wounds commenced the evaluation with wound-bed slough present and at 4 weeks 100% were deemed slough free. At a further 4-week review no patients wounds had regressed.
CONCLUSION:
The incorporation of a haemoglobin spray solution within this cohort of DFU resulted in a positive improvement in wound healing and slough elimination. Further work in this area is recommended to increase the evidence.
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NewsBot · Jul 7, 2015

Appropriate use of topical haemoglobin in chronic wound management: consensus recommendations.
CHADWICK, PAUL; MCCARDLE, JOANNE; MOHAMUD, LUXMI; TICKLE, JOY; VOWDEN, KATH; VOWDEN, PETER
Wounds UK . 2015 Special Issue, p30-35. 4p.

Oxygen has a crucial role in wound healing; 97% of chronic, non-healing wounds have been shown to have low oxygen levels (Hauser, 1987). Topical oxygen therapy has been shown to be effective in treating non-healing wounds, but is still underutilised. A working group of key opinion leaders met in February 2015 to determine the potential role of topical haemoglobin in non-healing wounds and to develop a clear decision-making pathway for clinical practice, as well as sharing practical tips for use. The group's consensus recommendations on appropriate use are presented here.
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NewsBot · Jul 7, 2015

Appropriate use of topical haemoglobin in chronic wound management: consensus recommendations.
CHADWICK, PAUL; MCCARDLE, JOANNE; MOHAMUD, LUXMI; TICKLE, JOY; VOWDEN, KATH; VOWDEN, PETER
Wounds UK . 2015 Special Issue, p30-35. 4p.

Oxygen has a crucial role in wound healing; 97% of chronic, non-healing wounds have been shown to have low oxygen levels (Hauser, 1987). Topical oxygen therapy has been shown to be effective in treating non-healing wounds, but is still underutilised. A working group of key opinion leaders met in February 2015 to determine the potential role of topical haemoglobin in non-healing wounds and to develop a clear decision-making pathway for clinical practice, as well as sharing practical tips for use. The group's consensus recommendations on appropriate use are presented here.
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