Vitamin D and verrucae

NewsBot · Aug 30, 2021

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Diagnostic and therapeutic implications of vitamin D deficiency
in patients with warts: A case-controlled study
Mamoun E. Shalaby et al
J Cosmet Dermatol. 2021;00:1–8.

Background: Cutaneous warts are frequent conditions that possess much challenge
to treat.
Objective: To verify the potential role of vitamin D in the pathogenesis of viral warts
by measuring the serum levels of vitamin D in patients diagnosed with viral warts
compared to healthy controls and to verify whether oral vitamin D supplementation
of those vitamin D-deficient patients would result in wart clearance.
Methods: To evaluate the serum vitamin D levels, the study recruited 80 subjects,
including 40 patients diagnosed with viral warts and 40 age- and sex-matched healthy
controls. All patients were subjected to detailed history taking and examination to detect duration and type of warts. Serum vitamin D levels were measured using ELISA.
Results: Thirty-five percent of patients had sufficient vitamin D levels (54–90 nmol/L),
and 40% of patients had insufficient levels (50–80 nmol/L), while 25% of them had
deficient levels (<50 nmol/L). In healthy group, 30% had sufficient levels, and 45% had
insufficient levels, while 25% had deficient levels. There was an insignificantly lower
serum level of vitamin D as well as an insignificantly deficient vitamin D status among
patients compared to healthy controls.
Conclusion: Vitamin D serum levels appear to be lower among viral wart patients, and
oral supplementation studies need to be more intensely investigated before elucidating its role; if any, in wart clearance.
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NewsBot · Aug 30, 2021

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