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Ten years of Charcot: what have we learned?

Discussion in 'Diabetic Foot & Wound Management' started by NewsBot, Feb 2, 2008.

  1. NewsBot

    NewsBot The Admin that posts the news.


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    The Thomson Newsroom have released this from the Diabetic Foot:

    Ten years of Charcot: what have we learned?
    By: Edmonds, Mike, Petrova, Nina
    Full article
     
  2. Admin2

    Admin2 Administrator Staff Member

  3. Aussie_Bec

    Aussie_Bec Member

    i dont really know where to post this to, but...

    i have a patient 57yo F with 4 month hx of diffuse dorsal midfoot pain. She thought her new brooks shoes were too aggressive. I recommended she get a more cushioning shoe (rigid painful foot on ROM testing). and sent her for xrays. She is obese but no history of diabetes etc.

    Xrays came back today.... Right foot: weightbearing pes planus. Advanced midfoot degeneration with hypertrophic new bone formation particularly around intercuneiform joints. There is subarticular cyst formation and advanced joint space reduction at tarsometatarsal joints, especially 2 and 3.

    Hallux MTP joint degeneration with subarticular cyst formation and mild HAV.

    Left: Normal joint alignment. mod-severe mid foot joint degeneration although less than R. preserved medial longitudinal arch on wb. there is a degree of naviculocuneiform degeneration. Increased sclerosis with loss of joint space 2nd/3rd ray TMT joints. NO HAV but significant MTP joint degeneration.

    This sounds and looks like charcot neuroarthropathy to me, but she doesnt have diabetes. Can you have Charcot without diabetes?
     
  4. DSP

    DSP Active Member

    Yes you can. But I beleive there has to be some form of peripheral neuropathy present.

    Is she alcohol dependant? Has she had bone density tests taken recently i.e. osteoporosis? How are her vascular and neurological tests? Was there anything there, particularly neurologically wise, which would be more indicative of the pt having a Charcot foot?
     
  5. NewsBot

    NewsBot The Admin that posts the news.

    Charcot neuro-osteoarthropathy-current standards.
    Petrova NL, Edmonds ME.
    Diabetes Metab Res Rev. 2008 Apr 29;24(S1):S58-S61 [Epub ahead of print]
     
  6. NewsBot

    NewsBot The Admin that posts the news.

    Magnetic resonance imaging in early stage charcot arthropathy - correlation of imaging findings and clinical symptoms.
    Schlossbauer T, Mioc T, Sommerey S, Kessler SB, Reiser MF, Pfeifer KJ.
    Eur J Med Res. 2008 Sep 22;13(9):409-14
     
  7. NewsBot

    NewsBot The Admin that posts the news.

    Charcot Arthropathy Risk Elevation in the Obese Diabetic Population
    Rodney M. Stuck, Min-Woong Sohn, Elly Budiman-Mak, Todd A. Lee and Kevin B. Weiss
    The American Journal of Medicine; Volume 121, Issue 11, November 2008, Pages 1008-1014
     
  8. NewsBot

    NewsBot The Admin that posts the news.

    Marked loss of sympathetic nerve fibers in chronic Charcot foot of diabetic origin compared to ankle joint osteoarthritis.
    Koeck FX, Bobrik V, Fassold A, Grifka J, Kessler S, Straub RH.
    J Orthop Res. 2008 Nov 21. [Epub ahead of print]
     
  9. NewsBot

    NewsBot The Admin that posts the news.

    Charcot neuroarthropathy triggered by osteomyelitis and/or surgery.
    Ndip A, Jude EB, Whitehouse R, Prescott M, Boulton AJ.
    Diabet Med. 2008 Dec;25(12):1469-72.
     
  10. NewsBot

    NewsBot The Admin that posts the news.

    Charcot arthropathy risk elevation in the obese diabetic population.
    Stuck RM, Sohn MW, Budiman-Mak E, Lee TA, Weiss KB.
    Am J Med. 2008 Nov;121(11):1008-14.
     
  11. NewsBot

    NewsBot The Admin that posts the news.

    Use of platelet-rich concentrate and bone marrow aspirate in high-risk patients with charcot arthropathy of the foot.
    Pinzur MS.
    Foot Ankle Int. 2009 Feb;30(2):124-7.
     
  12. NewsBot

    NewsBot The Admin that posts the news.

    Lower-Extremity Amputation Risk Following Charcot Arthropathy and Diabetic Foot Ulcer.
    Sohn MW, Stuck RM, Pinzur M, Lee TA, Budiman-Mak E.
    Diabetes Care. 2009 Oct 13. [Epub ahead of print]
     
  13. NewsBot

    NewsBot The Admin that posts the news.

    Pro-inflammatory modulation of the surface and cytokine phenotype of monocytes in patients with acute Charcot foot.
    Uccioli L, Sinistro A, Almerighi C, Ciaprini C, Cavazza A, Giurato L, Ruotolo V, Spasaro F, Vainieri E, Rocchi G, Bergamini A.
    Diabetes Care. 2009 Oct 30. [Epub ahead of print]
     
  14. NewsBot

    NewsBot The Admin that posts the news.

    The Role of Quantitative Bone Scanning in the Assessment of Bone Turnover in Patients with Charcot Foot.
    Bem R, Jirkovská A, Dubsky M, Fejfarová V, Buncová M, Skibová J, Jude EB.
    Diabetes Care. 2009 Nov 23. [Epub ahead of print]
     
  15. NewsBot

    NewsBot The Admin that posts the news.

    Bone mineral density in diabetes mellitus patients with and without a Charcot foot.
    Christensen TM, Bülow J, Simonsen L, Holstein PE, Svendsen OL.
    Clin Physiol Funct Imaging. 2010 Jan 18.
     
  16. NewsBot

    NewsBot The Admin that posts the news.

    Role of Quantitative Bone Scanning in the Assessment of Bone Turnover in Patients With Charcot Foot
    Robert Bem, Alexandra Jirkovská, Michal Dubský, Vladimira Fejfarová, Marie Buncová, Jelena Skibová, and Edward B. Jude
    Diabetes Care February 2010 vol. 33 no. 2 348-349
     
  17. NewsBot

    NewsBot The Admin that posts the news.

    Charcot's foot: Newest findings on its pathophysiology, diagnosis and treatment.
    Molines L, Darmon P, Raccah D.
    Diabetes Metab. 2010 Jun 4. [Epub ahead of print]
     
  18. NewsBot

    NewsBot The Admin that posts the news.

    A Prospective Study of Calcaneal Bone Mineral Density in Acute Charcot Osteoarthropathy.
    Petrova NL, Edmonds ME.
    Diabetes Care. 2010 Jul 13. [Epub ahead of print]
     
  19. NewsBot

    NewsBot The Admin that posts the news.

    Triggering mechanisms of neuroarthropathy following conservative surgery for osteomyelitis.
    Aragón-Sánchez J, Lázaro-Martínez JL, Hernández-Herrero MJ.
    Diabet Med. 2010 Jul;27(7):844-7.
     
  20. NewsBot

    NewsBot The Admin that posts the news.

    A Prospective Study of Calcaneal Bone Mineral Density in Acute Charcot Osteoarthropathy
    Nina L. Petrova & Michael E. Edmonds
    Diabetes Care October 2010 vol. 33 no. 10 2254-2256
     
  21. NewsBot

    NewsBot The Admin that posts the news.

    The consequences of complacency: managing the effects of unrecognized Charcot feet.
    Wukich DK, Sung W, Wipf SA, Armstrong DG.
    Diabet Med. 2011 Feb;28(2):195-8.
     
  22. NewsBot

    NewsBot The Admin that posts the news.

    Role of Dynamic MRI in the follow-up of acute Charcot foot in patients with diabetes mellitus.
    Zampa V, Bargellini I, Rizzo L, Turini F, Ortori S, Piaggesi A, Bartolozzi C.
    Skeletal Radiol. 2011 Jan 28. [Epub ahead of print]
     
  23. NewsBot

    NewsBot The Admin that posts the news.

    The Effect of Zoledronic Acid on the Clinical Resolution of Charcot Neuroarthropathy: A pilot randomized controlled trial.
    Pakarinen TK, Laine HJ, Mäenpää H, Mattila P, Lahtela J.
    Diabetes Care. 2011 May 18. [Epub ahead of print]
     
  24. NewsBot

    NewsBot The Admin that posts the news.

    Trabecular Quality and Cellular Characteristics of Normal, Diabetic, and Charcot Bone
    Javier La Fontaine, Naohiro Shibuya, H. Wayne Sampson, Maria Del Pilar Valderrama
    Journal of Foot and Ankle Surgery (published online first)
     
  25. NewsBot

    NewsBot The Admin that posts the news.

    Osteoprotegerin gene polymorphism in diabetic Charcot neuroarthropathy.
    Korzon-Burakowska A, Jakóbkiewicz-Banecka J, Fiedosiuk A, Petrova N, Koblik T, Gabig-Cimińska M, Edmonds M, Małecki MT, Węgrzyn G.
    Diabet Med. 2011 Sep 13.
     
  26. NewsBot

    NewsBot The Admin that posts the news.

    Sympathetic neuropathy in diabetes mellitus patients does not elicit Charcot osteoarthropathy
    Tomas M. Christensen, Lene Simonsen, Per E. Holstein, Ole L. Svendsen, Jens Bülow
    Journal of Diabetes and its Complications
    Volume 25, Issue 5, September-October 2011, Pages 320-324

     
  27. NewsBot

    NewsBot The Admin that posts the news.

    Audit of acute Charcot's disease in the UK: the CDUK study.
    Game FL, Catlow R, Jones GR, Edmonds ME, Jude EB, Rayman G, Jeffcoate WJ.
    Diabetologia. 2011 Nov 8.
     
  28. NewsBot

    NewsBot The Admin that posts the news.

    Audit of acute Charcot’s disease in the UK: the CDUK study
    F. L. Game, R. Catlow, G. R. Jones, M. E. Edmonds, E. B. Jude, G. Rayman and W. J. Jeffcoate
    Diabetologia Volume 55, Number 1, 32-35
     
  29. NewsBot

    NewsBot The Admin that posts the news.

    The pathogenesis of Charcot neuroarthropathy: current concepts
    Shelly A.M. Larson, Patrick R. Burns
    Diabetic Foot & Ankle 2012, 3:
     
  30. NewsBot

    NewsBot The Admin that posts the news.

    A Proposed Treatment Algorithm for Midfoot Charcot Arthropathy.
    Smith WB, Moore CA.
    Foot Ankle Spec. 2012 Jan 20
     
  31. pied-a-terre

    pied-a-terre Welcome New Poster

    Reading through the many posts in this and other threads brings to mind this question: Do any of you know if there has been a review of the literature regarding Charcot neuropathy in NON-diabetics? Aside from having some degree of neuropathy, what other traits do they generally share with diabetic Charcot patients and where do they differ?

    Also, has anyone seen anything written from the non-diabetic Charcot patient's perspective?

    Thanks much.
     
  32. NewsBot

    NewsBot The Admin that posts the news.

    Charcot foot: Skin temperature as a good clinical parameter for predicting disease outcome.
    Moura-Neto A, Fernandes TD, Zantut-Wittmann DE, Trevisan RO, Sakaki MH, Santos AL, Nery M, Parisi MC.
    Diabetes Res Clin Pract. 2012 Jan 30
     
  33. NewsBot

    NewsBot The Admin that posts the news.

    Doppler spectrum analysis: A potentially useful diagnostic tool for
    planning the treatment of patients with Charcot arthropathy of the foot?

    T. Wu, P-Y. Chen, C-H. Chen, and C-L. Wang
    J Bone Joint Surg Br 2012;94-B 344-347
     
  34. NewsBot

    NewsBot The Admin that posts the news.

    Diabetic Nephropathy but not HbA1c is Predictive for Frequent Complications of Charcot Feet - Long-term follow-up of 164 Consecutive Patients with 195 Acute Charcot Feet.
    Sämann A, Pofahl S, Lehmann T, Voigt B, Victor S, Möller F, Müller U, Wolf G.
    Exp Clin Endocrinol Diabetes. 2012 Mar 15.
     
  35. NewsBot

    NewsBot The Admin that posts the news.

    Charcot foot: Skin temperature as a good clinical parameter for predicting disease outcome
    Arnaldo Moura-Neto, Tulio Diniz Fernandes, Denise Engelbrecht Zantut-Wittmann, Rafael Ortiz Trevisan, Marcos Hideyo Sakaki, Alexandre Leme Godoy Santos, Marcia Nery, Maria Candid, Ribeiro Parisi
    Diabetes Research and Clinical Practice Volume 96, Issue 2, May 2012, Pages e11–e14
     
  36. NewsBot

    NewsBot The Admin that posts the news.

    Pressure pain thresholds at the diabetic Charcot-foot: an exploratory study.
    Chantelau E, Wienemann T, Richter A.
    J Musculoskelet Neuronal Interact. 2012 Jun;12(2):95-101.
     
  37. NewsBot

    NewsBot The Admin that posts the news.

    Peripheral and Central Bone Mineral Density in Charcot’s Neuroarthropathy Compared in Diabetic and Nondiabetic Populations
    Robert M. Greenhagen, Dane K. Wukich, Rachel H. Jung, Vassilios Vardaxis, Robert M. Yoho
    J Am Podiatr Med Assoc 102(3): 213–222, 2012
     
  38. NewsBot

    NewsBot The Admin that posts the news.

    Duration of off-loading and recurrence rate in Charcot osteo-arthropathy treated with less restrictive regimen with removable walker.
    Christensen TM, Gade-Rasmussen B, Pedersen LW, Hommel E, Holstein PE, Svendsen OL.
    J Diabetes Complications. 2012 Jun 12.
     
  39. NewsBot

    NewsBot The Admin that posts the news.

    Charcot arthropathy presenting with primary bone resorption.
    Jones CW, Agolley D, Burns K, Gupta S, Horsley M.
    Foot (Edinb). 2012 Jul 24.
     
  40. NewsBot

    NewsBot The Admin that posts the news.

    Medical management of Charcot Arthropathy.
    Petrova NL, Edmonds ME.
    Diabetes Obes Metab. 2012 Aug 1.
     
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